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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1994 May;57(5):594–596. doi: 10.1136/jnnp.57.5.594

Diffuse neurofibrillary tangles with calcification: a new presenile dementia.

K Kosaka 1
PMCID: PMC1072922  PMID: 8201331

Abstract

The term "diffuse neurofibrillary tangles with calcification" (DNTC) is proposed for a new form of presenile dementia. It is characterised by slowly progressive cortical dementia in the presenium, localised temporal or temporofrontal lobar atrophy, numerous neurofibrillary tangles widespread in the cerebral cortex, and pronounced calcareous deposits; 16 cases of DNTC, have been reported.

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Selected References

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