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. 1994 May;57(5):622–625. doi: 10.1136/jnnp.57.5.622

Are brief or recurrent transient global amnesias of epileptic origin?

T P Melo 1, J M Ferro 1, T Paiva 1
PMCID: PMC1072928  PMID: 8201337

Abstract

To evaluate if short (less than one hour) or recurrent, or both, episodes of transient global amnesia (TGA) have an epileptic origin or carry a subsequent risk of epilepsy a group of patients with these types of TGA attacks was studied. The group was selected from a prospective series of 103 patients with TGA. Sixteen patients had an episode lasting less than one hour, 13 had more than one episode, and five patients had both short and recurrent attacks. For each patient the number of recurrences was small (four or less) and they were separated by months or years. During short attacks of TGA many subjects showed other typical features of TGA including repeated questioning (12 subjects) and performance of purposeful complex acts (eight subjects). Twelve short attacks were closely related to a characteristic precipitating event. During follow up only one patient had a seizure (partial motor). No other association between either short or repeated attacks of TGA and past history of epilepsy or paroxysmal discharges were seen on the EEG. Short or recurrent, or both, attacks of TGA are not epileptic and do not carry a relevant risk of subsequent seizures.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Cole A. J., Gloor P., Kaplan R. Transient global amnesia: the electroencephalogram at onset. Ann Neurol. 1987 Dec;22(6):771–772. doi: 10.1002/ana.410220616. [DOI] [PubMed] [Google Scholar]
  2. FISHER C. M., ADAMS R. D. TRANSIENT GLOBAL AMNESIA. Acta Neurol Scand Suppl. 1964;40:SUPPL 9–1083. [PubMed] [Google Scholar]
  3. Guidotti M., Anzalone N., Morabito A., Landi G. A case-control study of transient global amnesia. J Neurol Neurosurg Psychiatry. 1989 Mar;52(3):320–323. doi: 10.1136/jnnp.52.3.320. [DOI] [PMC free article] [PubMed] [Google Scholar]
  4. Heathfield K. W., Croft P. B., Swash M. The syndrome of transient global amnesia. Brain. 1973 Dec;96(4):729–736. doi: 10.1093/brain/96.4.729. [DOI] [PubMed] [Google Scholar]
  5. Hodges J. R., Warlow C. P. Syndromes of transient amnesia: towards a classification. A study of 153 cases. J Neurol Neurosurg Psychiatry. 1990 Oct;53(10):834–843. doi: 10.1136/jnnp.53.10.834. [DOI] [PMC free article] [PubMed] [Google Scholar]
  6. Hodges J. R., Warlow C. P. The aetiology of transient global amnesia. A case-control study of 114 cases with prospective follow-up. Brain. 1990 Jun;113(Pt 3):639–657. doi: 10.1093/brain/113.3.639. [DOI] [PubMed] [Google Scholar]
  7. Jacome D. E. EEG features in transient global amnesia. Clin Electroencephalogr. 1989 Jul;20(3):183–192. doi: 10.1177/155005948902000312. [DOI] [PubMed] [Google Scholar]
  8. Kushner M. J., Hauser W. A. Transient global amnesia: a case-control study. Ann Neurol. 1985 Dec;18(6):684–691. doi: 10.1002/ana.410180610. [DOI] [PubMed] [Google Scholar]
  9. Melo T. P., Ferro J. M., Ferro H. Transient global amnesia. A case control study. Brain. 1992 Feb;115(Pt 1):261–270. doi: 10.1093/brain/115.1.261. [DOI] [PubMed] [Google Scholar]
  10. Miller J. W., Yanagihara T., Petersen R. C., Klass D. W. Transient global amnesia and epilepsy. Electroencephalographic distinction. Arch Neurol. 1987 Jun;44(6):629–633. doi: 10.1001/archneur.1987.00520180049015. [DOI] [PubMed] [Google Scholar]
  11. Palmini A. L., Gloor P., Jones-Gotman M. Pure amnestic seizures in temporal lobe epilepsy. Definition, clinical symptomatology and functional anatomical considerations. Brain. 1992 Jun;115(Pt 3):749–769. doi: 10.1093/brain/115.3.749. [DOI] [PubMed] [Google Scholar]
  12. Pritchard P. B., 3rd, Holmstrom V. L., Roitzsch J. C., Giacinto J. Epileptic amnesic attacks: benefit from antiepileptic drugs. Neurology. 1985 Aug;35(8):1188–1189. doi: 10.1212/wnl.35.8.1188. [DOI] [PubMed] [Google Scholar]
  13. Rowan A. J., Protass L. M. Transient global amnesia: clinical and electroencephalographic findings in 10 cases. Neurology. 1979 Jun;29(6):869–872. doi: 10.1212/wnl.29.6.869. [DOI] [PubMed] [Google Scholar]
  14. Shuping J. R., Rollinson R. D., Toole J. F. Transient global amnesia. Ann Neurol. 1980 Mar;7(3):281–285. doi: 10.1002/ana.410070313. [DOI] [PubMed] [Google Scholar]
  15. Stracciari A., Ciucci G., Bianchedi G., Rebucci G. G. Epileptic transient amnesia. Eur Neurol. 1990;30(3):176–179. doi: 10.1159/000117339. [DOI] [PubMed] [Google Scholar]
  16. Tassinari C. A., Ciarmatori C., Alesi C., Cardinaletti L., Salvi F., Rubboli G., Plasmati R., Forti A., Michelucci R. Transient global amnesia as a postictal state from recurrent partial seizures. Epilepsia. 1991 Nov-Dec;32(6):882–885. doi: 10.1111/j.1528-1157.1991.tb05545.x. [DOI] [PubMed] [Google Scholar]

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