Skip to main content
PMC home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1994 Jun;57(6):705–708. doi: 10.1136/jnnp.57.6.705

Antibiotic induced meningitis.

Y River 1, L Averbuch-Heller 1, M Weinberger 1, Z Meiner 1, D Mevorach 1, I Schlesinger 1, Z Argov 1
PMCID: PMC1072974  PMID: 8006651

Abstract

Three patients with antibiotic induced meningitis, one following penicillin with seven episodes, are reported on--the first well documented description of penicillin induced meningitis. In this patient episodes of headache and nuchal rigidity appeared with and without CSF pleocytosis. Two patients had a total of five episodes of antibiotic induced meningitis after trimethoprim-sulphamethoxazole (co-trimoxazole) administration. The features common to all three patients were myalgia, confusion and low CSF glucose. CSF analysis was not a reliable method to differentiate antibiotic induced meningitis from partially treated bacterial meningitis.

Full text

PDF
705

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Asperilla M. O., Smego R. A., Jr Eosinophilic meningitis associated with ciprofloxacin. Am J Med. 1989 Nov;87(5):589–590. doi: 10.1016/s0002-9343(89)80620-5. [DOI] [PubMed] [Google Scholar]
  2. Biosca M., de la Figuera M., García-Bragado F., Sampol G. Aseptic meningitis due to trimethoprim-sulfamethoxazole. J Neurol Neurosurg Psychiatry. 1986 Mar;49(3):332–333. doi: 10.1136/jnnp.49.3.332. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Carlson J., Wiholm B. E. Trimethoprim associated aseptic meningitis. Scand J Infect Dis. 1987;19(6):687–691. doi: 10.3109/00365548709117205. [DOI] [PubMed] [Google Scholar]
  4. Casteels-Van Daele M., Wijndaele L., Hanninck K., Gillis P. Intravenous immune globulin and acute aseptic meningitis. N Engl J Med. 1990 Aug 30;323(9):614–615. [PubMed] [Google Scholar]
  5. Chez M., Sila C. A., Ransohoff R. M., Longworth D. L., Weida C. Ibuprofen-induced meningitis: detection of intrathecal IgG synthesis and immune complexes. Neurology. 1989 Dec;39(12):1578–1580. doi: 10.1212/wnl.39.12.1578. [DOI] [PubMed] [Google Scholar]
  6. Derbes S. J. Trimethoprim-induced aseptic meningitis. JAMA. 1984 Nov 23;252(20):2865–2866. [PubMed] [Google Scholar]
  7. Escalante A., Stimmler M. M. Trimethoprim-sulfamethoxasole induced meningitis in systemic lupus erythematosus. J Rheumatol. 1992 May;19(5):800–802. [PubMed] [Google Scholar]
  8. FARMER L., ECHLIN F. A., LOUGHLIN W. C., BREAKEY A. S., DUVOISIN R. Pachymeningitis apparently due to penicillin hypersensitivity. Ann Intern Med. 1960 Apr;52:910–914. doi: 10.7326/0003-4819-52-4-910. [DOI] [PubMed] [Google Scholar]
  9. Garagusi V. F., Neefe L. I., Mann O. Acute meningoencephalitis. Association with isoniazid administration. JAMA. 1976 Mar 15;235(11):1141–1142. doi: 10.1001/jama.235.11.1141. [DOI] [PubMed] [Google Scholar]
  10. Gordon M. F., Allon M., Coyle P. K. Drug-induced meningitis. Neurology. 1990 Jan;40(1):163–164. doi: 10.1212/wnl.40.1.163. [DOI] [PubMed] [Google Scholar]
  11. Joffe A. M., Farley J. D., Linden D., Goldsand G. Trimethoprim-sulfamethoxazole-associated aseptic meningitis: case reports and review of the literature. Am J Med. 1989 Sep;87(3):332–338. doi: 10.1016/s0002-9343(89)80160-3. [DOI] [PubMed] [Google Scholar]
  12. Kremer I., Ritz R., Brunner F. Aseptic meningitis as an adverse effect of co-trimoxazole. N Engl J Med. 1983 Jun 16;308(24):1481–1481. doi: 10.1056/NEJM198306163082415. [DOI] [PubMed] [Google Scholar]
  13. Marinac J. S. Drug- and chemical-induced aseptic meningitis: a review of the literature. Ann Pharmacother. 1992 Jun;26(6):813–822. doi: 10.1177/106002809202600613. [DOI] [PubMed] [Google Scholar]
  14. Samuelson C. O., Jr, Williams H. J. Ibuprofen-associated aseptic meningitis in systemic lupus erythematosus. West J Med. 1979 Jul;131(1):57–59. [PMC free article] [PubMed] [Google Scholar]
  15. Saxon A., Beall G. N., Rohr A. S., Adelman D. C. Immediate hypersensitivity reactions to beta-lactam antibiotics. Ann Intern Med. 1987 Aug;107(2):204–215. doi: 10.7326/0003-4819-107-2-204. [DOI] [PubMed] [Google Scholar]
  16. Shoenfeld Y., Livni E., Shaklai M., Pinkhas J. Sensitization to ibuprofen in systemic lupus erythematosus. JAMA. 1980 Aug 8;244(6):547–548. [PubMed] [Google Scholar]
  17. Stratton M. A. Drug-induced systemic lupus erythematosus. Clin Pharm. 1985 Nov-Dec;4(6):657–663. [PubMed] [Google Scholar]
  18. Widener H. L., Littman B. H. Ibuprofen-induced meningitis in systemic lupus erythematosus. JAMA. 1978 Mar 13;239(11):1062–1064. [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES