Suppression of Type 2 responses maintained upon oral exposure prior to vaccination with various adjuvants
Experimental timeline from Figure 1A was used with various adjuvants.
(A) OVA-IgG1 titers and secreted IL-4 upon OVA-re-stimulation of splenocytes after 72 h.
(B) OVA-IgG2c titers and secreted IFNγ upon OVA-re-stimulation of splenocytes after 72 h.
For each adjuvant, data are pooled from 2 to 3 independent experiments and represented as mean ± SD. Unpaired t tests were used for statistical analysis. ∗p < 0.05, ∗∗p < 0.01, ∗∗∗p < 0.001, ∗∗∗∗p < 0.0001.