Abstract
Twenty three patients with hemiballism and two with biballism were studied. Ischaemic and haemorrhagic strokes were the cause in most patients. Other causes were encephalitis, Sydenham's chorea, systemic lupus erythematosus, basal ganglia calcifications, non-ketotic hyperglycaemia, and tuberous sclerosis. Neuroimaging studies showed a lesion of the subthalamic nucleus in only six patients. In others, different subcortical structures were involved or the results were normal. Only two patients had "pure" hemiballism. The others had other types of dyskinesias, mainly chorea, which was present in 16 patients. The prognosis was usually good.
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- Aziz T. Z., Peggs D., Sambrook M. A., Crossman A. R. Lesion of the subthalamic nucleus for the alleviation of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced parkinsonism in the primate. Mov Disord. 1991;6(4):288–292. doi: 10.1002/mds.870060404. [DOI] [PubMed] [Google Scholar]
- BEDWELL S. F. Some observations on hemiballismus. Neurology. 1960 Jun;10:619–622. doi: 10.1212/wnl.10.6.619. [DOI] [PubMed] [Google Scholar]
- Bergman H., Wichmann T., DeLong M. R. Reversal of experimental parkinsonism by lesions of the subthalamic nucleus. Science. 1990 Sep 21;249(4975):1436–1438. doi: 10.1126/science.2402638. [DOI] [PubMed] [Google Scholar]
- Crossman A. R., Sambrook M. A., Jackson A. Experimental hemiballismus in the baboon produced by injection of a gamma-aminobutyric acid antagonist into the basal ganglia. Neurosci Lett. 1980 Dec;20(3):369–372. doi: 10.1016/0304-3940(80)90176-7. [DOI] [PubMed] [Google Scholar]
- Crossman A. R., Sambrook M. A., Jackson A. Experimental hemichorea/hemiballismus in the monkey. Studies on the intracerebral site of action in a drug-induced dyskinesia. Brain. 1984 Jun;107(Pt 2):579–596. doi: 10.1093/brain/107.2.579. [DOI] [PubMed] [Google Scholar]
- Dewey R. B., Jr, Jankovic J. Hemiballism-hemichorea. Clinical and pharmacologic findings in 21 patients. Arch Neurol. 1989 Aug;46(8):862–867. doi: 10.1001/archneur.1989.00520440044020. [DOI] [PubMed] [Google Scholar]
- Evans B. K., Jankovic J. Tuberous sclerosis and chorea. Ann Neurol. 1983 Jan;13(1):106–107. doi: 10.1002/ana.410130125. [DOI] [PubMed] [Google Scholar]
- Friedman J. H. A case of progressive hemichorea responsive to high-dose reserpine. J Clin Psychiatry. 1986 Mar;47(3):149–150. [PubMed] [Google Scholar]
- Glass J. P., Jankovic J., Borit A. Hemiballism and metastatic brain tumor. Neurology. 1984 Feb;34(2):204–207. doi: 10.1212/wnl.34.2.204. [DOI] [PubMed] [Google Scholar]
- Greenamyre J. T., O'Brien C. F. N-methyl-D-aspartate antagonists in the treatment of Parkinson's disease. Arch Neurol. 1991 Sep;48(9):977–981. doi: 10.1001/archneur.1991.00530210109030. [DOI] [PubMed] [Google Scholar]
- HYLAND H. H., FORMAN D. M. Prognosis in hemiballismus. Neurology. 1957 Jun;7(6):381–391. doi: 10.1212/wnl.7.6.381. [DOI] [PubMed] [Google Scholar]
- Inbody S., Jankovic J. Hyperkinetic mutism: bilateral ballism and basal ganglia calcification. Neurology. 1986 Jun;36(6):825–827. doi: 10.1212/wnl.36.6.825. [DOI] [PubMed] [Google Scholar]
- Johnson W. G., Fahn S. Treatment of vascular hemiballism and hemichorea. Neurology. 1977 Jul;27(7):634–636. doi: 10.1212/wnl.27.7.634. [DOI] [PubMed] [Google Scholar]
- Kase C. S., Maulsby G. O., deJuan E., Mohr J. P. Hemichorea-hemiballism and lacunar infarction in the basal ganglia. Neurology. 1981 Apr;31(4):452–455. doi: 10.1212/wnl.31.4.452. [DOI] [PubMed] [Google Scholar]
- Klawans H. L., Moses H., 3rd, Nausieda P. A., Bergen D., Weiner W. J. Treatment and prognosis of hemiballismus. N Engl J Med. 1976 Dec 9;295(24):1348–1350. doi: 10.1056/NEJM197612092952404. [DOI] [PubMed] [Google Scholar]
- LEMMEN L. J., DAVIS J. S., FISHER E. R. Hemiballismus secondary to metastatic carcinoma of the gall bladder. Neurology. 1957 Dec;7(12):873–874. doi: 10.1212/wnl.7.12.873. [DOI] [PubMed] [Google Scholar]
- Lang A. E. Persistent hemiballismus with lesions outside the subthalamic nucleus. Can J Neurol Sci. 1985 May;12(2):125–128. doi: 10.1017/s0317167100046825. [DOI] [PubMed] [Google Scholar]
- Lobo-Antunes J., Yahr M. D., Hilal S. K. Extrapyramidal dysfunction with cerebral arteriovenous malformations. J Neurol Neurosurg Psychiatry. 1974 Mar;37(3):259–268. doi: 10.1136/jnnp.37.3.259. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Lodder J., Baard W. C. Paraballism caused by bilateral hemorrhagic infarction in basal ganglia. Neurology. 1981 Apr;31(4):484–486. doi: 10.1212/wnl.31.4_part_2.484. [DOI] [PubMed] [Google Scholar]
- MARTIN J. P. Hemichorea (hemiballismus) without lesions in the corpus Luysii. Brain. 1957 Mar;80(1):1–10. doi: 10.1093/brain/80.1.1. [DOI] [PubMed] [Google Scholar]
- MEYERS R., SWEENEY D. B., SCHWIDDE J. T. Hemiballismus: aetiology and surgical treatment. J Neurol Neurosurg Psychiatry. 1950 May;13(2):115–126. doi: 10.1136/jnnp.13.2.115. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Margolin D. I., Marsden C. D. Episodic dyskinesias and transient cerebral ischemia. Neurology. 1982 Dec;32(12):1379–1380. doi: 10.1212/wnl.32.12.1379. [DOI] [PubMed] [Google Scholar]
- Masucci E. F., Saini N., Kurtzke J. F. Bilateral ballism in multiple sclerosis. Neurology. 1989 Dec;39(12):1641–1642. doi: 10.1212/wnl.39.12.1641. [DOI] [PubMed] [Google Scholar]
- Melamed E., Korn-Lubetzki I., Reches A., Siew F. Hemiballismus: detection of focal hemorrhage in subthalamic nucleus by CT scan. Ann Neurol. 1978 Dec;4(6):582–582. doi: 10.1002/ana.410040627. [DOI] [PubMed] [Google Scholar]
- Modesti L. M., Van Buren J. M. Hemiballismus complicating stereotactic thalamotomy. Appl Neurophysiol. 1979;42(5):267–283. doi: 10.1159/000102374. [DOI] [PubMed] [Google Scholar]
- Nath A., Jankovic J., Pettigrew L. C. Movement disorders and AIDS. Neurology. 1987 Jan;37(1):37–41. doi: 10.1212/wnl.37.1.37. [DOI] [PubMed] [Google Scholar]
- Nausieda P. A., Koller W. C., Weiner W. J., Klawans H. L. Chorea induced by oral contraceptives. Neurology. 1979 Dec;29(12):1605–1609. doi: 10.1212/wnl.29.12.1605. [DOI] [PubMed] [Google Scholar]
- Obeso J. A., Marti-Masso J. F., Astudillo W., de la Puente E., Carrera N. Treatment with hemiballism with reserpine. Ann Neurol. 1978 Dec;4(6):581–581. doi: 10.1002/ana.410040626. [DOI] [PubMed] [Google Scholar]
- Opida C. L., Korthals J. K., Somasundaram M. Bilateral ballismus in phenytoin intoxication. Ann Neurol. 1978 Feb;3(2):186–186. doi: 10.1002/ana.410030219. [DOI] [PubMed] [Google Scholar]
- Penney J. B., Jr, Young A. B. Striatal inhomogeneities and basal ganglia function. Mov Disord. 1986;1(1):3–15. doi: 10.1002/mds.870010102. [DOI] [PubMed] [Google Scholar]
- Rector W. G., Jr, Herlong H. F., Moses H., 3rd Nonketotic hyperglycemia appearing as choreoathetosis or ballism. Arch Intern Med. 1982 Jan;142(1):154–155. [PubMed] [Google Scholar]
- Riley D., Lang A. E. Hemiballism in multiple sclerosis. Mov Disord. 1988;3(1):88–94. doi: 10.1002/mds.870030111. [DOI] [PubMed] [Google Scholar]
- SATTES H. [The treatment of chorea minor with the monoamine liberator "Nitoman"]. Psychiatr Neurol (Basel) 1960 Jul;140:13–19. [PubMed] [Google Scholar]
- Saris S. Chorea caused by caudate infarction. Arch Neurol. 1983 Sep;40(9):590–591. doi: 10.1001/archneur.1983.04050080090021. [DOI] [PubMed] [Google Scholar]
- Sellal F., Hirsch E., Lisovoski F., Mutschler V., Collard M., Marescaux C. Contralateral disappearance of parkinsonian signs after subthalamic hematoma. Neurology. 1992 Jan;42(1):255–256. doi: 10.1212/wnl.42.1.255. [DOI] [PubMed] [Google Scholar]
- Shannon K. M. Hemiballismus. Clin Neuropharmacol. 1990 Oct;13(5):413–425. doi: 10.1097/00002826-199010000-00003. [DOI] [PubMed] [Google Scholar]
- THOMPSON H. G., Jr, CARPENTER M. B. Hemichorea due to metastatic lesion in the subthalamic nucleus. Arch Neurol. 1960 Feb;2:183–187. doi: 10.1001/archneur.1960.03840080069011. [DOI] [PubMed] [Google Scholar]
- Tamaoka A., Sakuta M., Yamada H. Hemichorea-hemiballism caused by arteriovenous malformations in the putamen. J Neurol. 1987 Feb;234(2):124–125. doi: 10.1007/BF00314118. [DOI] [PubMed] [Google Scholar]
- Thompson S. W. Ballistic movements of the arm in systemic lupus erythematosis. Dis Nerv Syst. 1976 Jun;37(6):331–332. [PubMed] [Google Scholar]
- Wright R. A., Pollock M., Donaldson I. M. Chorea and tuberous sclerosis. Mov Disord. 1992;7(1):87–89. doi: 10.1002/mds.870070119. [DOI] [PubMed] [Google Scholar]