Skip to main content
. 2023 Dec 20;12:e94760. doi: 10.7554/eLife.94760

Figure 1. The effect of cannabis on embryonic stem cell types from mice.

Figure 1.

The psychoactive component of cannabis, ∆9-THC, alters the growth and metabolism of early embryonic cell types of mice. Treatment with ∆9-THC increased glycolysis in mouse embryonic stem cells (mESCs, pink circle) and epiblast-like cells (mEpiLCs, yellow shape). It also increased the proliferation rate of the mESCs, but not mEpiLCs. Primordial germ cell-like cells (mPGCLCs, blue circle) derived from the ∆9-THC-treated cells also showed increased rates of glycolysis, respiration and proliferation, even in the absence of ongoing ∆9-THC exposure.