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. 2023 Dec 6;15(1):2289769. doi: 10.1080/21505594.2023.2289769

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (http://creativecommons.org/licenses/by-nc/4.0/), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 6. — Molecular pathways induced by desiccation and starvation stresses in A. baumannii. desiccation and starvation stresses activate the two-component system BmfS/BmfR leading to the release of BmfR that acts as a transcriptional regulator. BmfR activates the expression of different genes, including those coding for the catalase KatE implicated in ROS detoxification, CsrA, an RNA-binding protein acting as a post-transcriptional regulator through modulation of the half-life of different mRnas, and the two hydrophilins DtpA and DtpB, acting as molecular chaperones that prevent protein denaturation. Denatured proteins that cannot be re-folded are degraded by the lon protease. Abbreviations: OM, outer membrane; P, periplasm; IM, inner membrane. Figure created with Biorender.