Skip to main content
PMC home page
Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1995 Feb;58(2):174–179. doi: 10.1136/jnnp.58.2.174

Neuropsychological pattern of striatonigral degeneration: comparison with Parkinson's disease and progressive supranuclear palsy.

B Pillon 1, N Gouider-Khouja 1, B Deweer 1, M Vidailhet 1, C Malapani 1, B Dubois 1, Y Agid 1
PMCID: PMC1073313  PMID: 7876847

Abstract

To study the neuropsychological pattern of striatonigral degeneration (SND), 14 consecutive patients with probable SND were submitted to an extensive battery of neuropsychological tests. Compared with controls the performance of patients with SND was impaired on category and phonemic fluency, frontal behaviours, trail making test A and B, and free recall of the Grober and Buschke test, but normal on the revised WAIS verbal scale, Raven 47 coloured progressive matrices, Wechsler memory scale, California verbal learning test, Wisconsin card sorting test, and the Stroop interference condition. The performance of patients with SND was also compared with that of 14 patients with Parkinson's disease and 14 patients with progressive supranuclear palsy (PSP) matched for age at onset, duration of disease, severity of intellectual deterioration, and depression. The results showed that the dysexecutive syndrome of SND is similar to that of Parkinson's disease and less severe than in PSP.

Full text

PDF
174

Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alexander G. E., DeLong M. R., Strick P. L. Parallel organization of functionally segregated circuits linking basal ganglia and cortex. Annu Rev Neurosci. 1986;9:357–381. doi: 10.1146/annurev.ne.09.030186.002041. [DOI] [PubMed] [Google Scholar]
  2. Bannister R., Oppenheimer D. R. Degenerative diseases of the nervous system associated with autonomic failure. Brain. 1972;95(3):457–474. doi: 10.1093/brain/95.3.457. [DOI] [PubMed] [Google Scholar]
  3. Blin J., Baron J. C., Dubois B., Pillon B., Cambon H., Cambier J., Agid Y. Positron emission tomography study in progressive supranuclear palsy. Brain hypometabolic pattern and clinicometabolic correlations. Arch Neurol. 1990 Jul;47(7):747–752. doi: 10.1001/archneur.1990.00530070035009. [DOI] [PubMed] [Google Scholar]
  4. Brooks D. J., Salmon E. P., Mathias C. J., Quinn N., Leenders K. L., Bannister R., Marsden C. D., Frackowiak R. S. The relationship between locomotor disability, autonomic dysfunction, and the integrity of the striatal dopaminergic system in patients with multiple system atrophy, pure autonomic failure, and Parkinson's disease, studied with PET. Brain. 1990 Oct;113(Pt 5):1539–1552. doi: 10.1093/brain/113.5.1539. [DOI] [PubMed] [Google Scholar]
  5. Eslinger P. J., Grattan L. M. Frontal lobe and frontal-striatal substrates for different forms of human cognitive flexibility. Neuropsychologia. 1993 Jan;31(1):17–28. doi: 10.1016/0028-3932(93)90077-d. [DOI] [PubMed] [Google Scholar]
  6. Fearnley J. M., Lees A. J. Striatonigral degeneration. A clinicopathological study. Brain. 1990 Dec;113(Pt 6):1823–1842. doi: 10.1093/brain/113.6.1823. [DOI] [PubMed] [Google Scholar]
  7. Folstein M. F., Folstein S. E., McHugh P. R. "Mini-mental state". A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res. 1975 Nov;12(3):189–198. doi: 10.1016/0022-3956(75)90026-6. [DOI] [PubMed] [Google Scholar]
  8. Fujita T., Doi M., Ogata T., Kanazawa I., Mizusawa H. Cerebral cortical pathology of sporadic olivopontocerebellar atrophy. J Neurol Sci. 1993 May;116(1):41–46. doi: 10.1016/0022-510x(93)90087-f. [DOI] [PubMed] [Google Scholar]
  9. Grober E., Buschke H., Crystal H., Bang S., Dresner R. Screening for dementia by memory testing. Neurology. 1988 Jun;38(6):900–903. doi: 10.1212/wnl.38.6.900. [DOI] [PubMed] [Google Scholar]
  10. Lhermitte F., Pillon B., Serdaru M. Human autonomy and the frontal lobes. Part I: Imitation and utilization behavior: a neuropsychological study of 75 patients. Ann Neurol. 1986 Apr;19(4):326–334. doi: 10.1002/ana.410190404. [DOI] [PubMed] [Google Scholar]
  11. Milner B. Some cognitive effects of frontal-lobe lesions in man. Philos Trans R Soc Lond B Biol Sci. 1982 Jun 25;298(1089):211–226. doi: 10.1098/rstb.1982.0083. [DOI] [PubMed] [Google Scholar]
  12. Montgomery S. A., Asberg M. A new depression scale designed to be sensitive to change. Br J Psychiatry. 1979 Apr;134:382–389. doi: 10.1192/bjp.134.4.382. [DOI] [PubMed] [Google Scholar]
  13. Nelson H. E. A modified card sorting test sensitive to frontal lobe defects. Cortex. 1976 Dec;12(4):313–324. doi: 10.1016/s0010-9452(76)80035-4. [DOI] [PubMed] [Google Scholar]
  14. Perret E. The left frontal lobe of man and the suppression of habitual responses in verbal categorical behaviour. Neuropsychologia. 1974 Jul;12(3):323–330. doi: 10.1016/0028-3932(74)90047-5. [DOI] [PubMed] [Google Scholar]
  15. Pillon B., Deweer B., Agid Y., Dubois B. Explicit memory in Alzheimer's, Huntington's, and Parkinson's diseases. Arch Neurol. 1993 Apr;50(4):374–379. doi: 10.1001/archneur.1993.00540040036010. [DOI] [PubMed] [Google Scholar]
  16. Pillon B., Deweer B., Michon A., Malapani C., Agid Y., Dubois B. Are explicit memory disorders of progressive supranuclear palsy related to damage to striatofrontal circuits? Comparison with Alzheimer's, Parkinson's, and Huntington's diseases. Neurology. 1994 Jul;44(7):1264–1270. doi: 10.1212/wnl.44.7.1264. [DOI] [PubMed] [Google Scholar]
  17. Pillon B., Dubois B., Ploska A., Agid Y. Severity and specificity of cognitive impairment in Alzheimer's, Huntington's, and Parkinson's diseases and progressive supranuclear palsy. Neurology. 1991 May;41(5):634–643. doi: 10.1212/wnl.41.5.634. [DOI] [PubMed] [Google Scholar]
  18. Quinn N. Multiple system atrophy--the nature of the beast. J Neurol Neurosurg Psychiatry. 1989 Jun;Suppl:78–89. doi: 10.1136/jnnp.52.suppl.78. [DOI] [PMC free article] [PubMed] [Google Scholar]
  19. Robbins T. W., James M., Lange K. W., Owen A. M., Quinn N. P., Marsden C. D. Cognitive performance in multiple system atrophy. Brain. 1992 Feb;115(Pt 1):271–291. doi: 10.1093/brain/115.1.271. [DOI] [PubMed] [Google Scholar]
  20. Spokes E. G., Bannister R., Oppenheimer D. R. Multiple system atrophy with autonomic failure: clinical, histological and neurochemical observations on four cases. J Neurol Sci. 1979 Sep;43(1):59–82. doi: 10.1016/0022-510x(79)90073-x. [DOI] [PubMed] [Google Scholar]
  21. Taylor A. E., Saint-Cyr J. A., Lang A. E. Frontal lobe dysfunction in Parkinson's disease. The cortical focus of neostriatal outflow. Brain. 1986 Oct;109(Pt 5):845–883. doi: 10.1093/brain/109.5.845. [DOI] [PubMed] [Google Scholar]

Articles from Journal of Neurology, Neurosurgery, and Psychiatry are provided here courtesy of BMJ Publishing Group

RESOURCES