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Journal of Inflammation (London, England) logoLink to Journal of Inflammation (London, England)
. 2023 Dec 20;20:45. doi: 10.1186/s12950-023-00370-x

Retraction Note: Valproic acid attenuates intercellular adhesion molecule-1 and E-selectin through a chemokine ligand 5 dependent mechanism and subarachnoid hemorrhage induced vasospasm in a rat model

Chih-Zen Chang 1,2,3,, Shu-Chuan Wu 2, Chih-Lung Lin 1,2, Aij-Lie Kwan 1,2
PMCID: PMC10734069  PMID: 38124080

Retraction Note: J Inflamm 12, 27 (2015)

https://doi.org/10.1186/s12950-015-0074-3

The Editors-in-Chief have retracted this article. After publication, concerns were raised regarding the data presented in the figures, specifically:

  • Fig. 1c appears highly similar to Fig. 1c of [1], Fig. 1b of [2] and Fig. 1c of [3].

  • Fig. 1f appears highly similar to Fig. 1f of [3].

  • Fig. 1c also appears highly similar to 1b in [4].

  • The b-actin blots across all figures appear highly similar (rotated in Fig. 4), although they represent different groups.

  • The b-actin blots also appear highly similar to b-actin in Fig. 3 and GAPDH in Fig. 4 of [5].

  • Sham data are not presented in Figs. 2-4.

  • SAH+V image is not included in Fig. 2.

  • The error bars in the graphs appear unusually consistent.

The Editors-in-Chief therefore no longer have confidence in the presented data.

None of the authors have responded to any correspondence from the publisher about this retraction.

References

  • 1.Chang CZ, Wu SC, Kwan AL, et al. Magnesium lithospermate B alleviates the production of endothelin-1 through an NO-dependent mechanism and reduces experimental vasospasm in rats. Acta Neurochir. 2011;153:2211–2217. doi: 10.1007/s00701-011-1082-6. [DOI] [PubMed] [Google Scholar]
  • 2.Chang CZ, Wu SC, Kwan AL. Magnesium lithospermate B, an active extract of Salvia miltiorrhiza , mediates sGC/cGMP/PKG translocation in experimental vasospasm. Biomed Res Int. 2014;2014:272101. doi: 10.1155/2014/272101. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 3.Chang CZ, Wu SC, Chang CM, et al. Arctigenin, a potent ingredient of Arctium lappa L., induces endothelial nitric oxide synthase and attenuates subarachnoid hemorrhage-induced vasospasm through PI3K/Akt pathway in a rat model. Biomed Res Int. 2015;2015:490209. doi: 10.1155/2015/490209. [DOI] [PMC free article] [PubMed] [Google Scholar]
  • 4.Chang CZ, Lin CL, Kassel NF, et al. 6-Mercaptopurine attenuates adhesive molecules in experimental vasospasm. Acta Neurochir. 2010;152:861–7. 10.1007/s00701-010-0602-0. [DOI] [PubMed]
  • 5.Chang CZ, Lin CL, Wu SC, Kwan AL. Purpurogallin, a natural phenol, attenuates high-mobility group box 1 in subarachnoid Hemorrhage induced vasospasm in a rat model. Int J Vasc Med. 2014;2014:254270. doi: 10.1155/2014/254270. [DOI] [PMC free article] [PubMed] [Google Scholar]

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