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The CRISPR cluster. The CRISPR-associated (Cas) cluster consists of genes coding for the needed proteins for the correct function of the system, such as Cas9, or adaptation-involved proteins (Cas1, Cas2, etc.). The leader sequence controls the expression of the CRISPR array when it becomes necessary; spacers are non-repetitive sequences that separate the repeats; and repeats are strongly conserved palindromic sequences capable of hairpin formation.
