Figure 6.

Comparison of [⁸⁹Zr]Zr-DFO-KN035 immunoPET imaging before and after treatment in patients with PD-L1-positive vascular lymphoma (Case No. 4). MIP and coronal section of the PET/CT images of a PD-L1 positive (TPS = 30%) patient (malignant vascular lymphoma) acquired through [⁸⁹Zr]Zr-DFO-KN035 immunoPET before (53 and 119 h) and after (53 and 124 h) combined anti-PD-1 therapy. The images show reductions in radioactive uptake at lymphoma focus sites at both time points. Red arrows show the locations of primary tumor and metastatic focus sites.