Fig. 3.

Predicted probabilities of obstructive phenotypes by gestational age and current wheeze. Points represent the predicted probability of each phenotype for each participant based on gestational age and current wheeze at the time of first lung function. The probabilities are estimated from a mixed-effect multinomial logistic regression model with gestational age, current wheeze, and its interaction as fixed effect covariates and cohort as a random effect. The outcome variable here is obstructive phenotype with four outcome categories, i.e., Normal, worsening, Improvement, and persistent obstruction.