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. Author manuscript; available in PMC: 2024 Jan 2.
Published in final edited form as: Biochemistry. 2023 Sep 20;62(24):3533–3547. doi: 10.1021/acs.biochem.3c00371

Figure 2. Post-synthesis stability of MC3 LNPs.

Figure 2.

MC3 LNP Cre mRNA (0.125 μg μL−1; stored at 4°C) was injected 24 hr, 48 hr and 1 month after the MC3 LNP synthesis into the striatum (Left) or hippocampus (Right) of Ai9 mice. The presence of tdTomato (red) expression and DAPI (blue) nuclear staining were analyzed 21 days after the MC3 LNP Cre mRNA injection. Scale bars represent 100 μm (Left) for whole brain images and 30 μm (Right) for higher magnification images, respectively.