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. 2023 Dec 18;10(1):e23915. doi: 10.1016/j.heliyon.2023.e23915

Fig. 2.

Fig. 2

The mutation landscape and regulation network of TLS genes. a. Landscape of genomic alterations in the TLS genes in cancer. Each row represents a gene, and each column represents a patient. The frequency of alterations in nine genes of TLS is presented. b. Distribution of mutation frequencies over cancer types. c. Distribution of amplification of SCNA frequencies over cancer types. d. Distribution of depletion of SCNA frequencies over cancer types. e. Correlation between methylation and TLS genes over cancer types. f. Circos plot showing the regulation of miRNA on TLS genes. G. Network plot showing the regulation of miRNA on TLS genes.