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. 2023 Sep 21;49(3):584–592. doi: 10.1038/s41386-023-01736-8

Fig. 2. Suicide-specific alterations in the kynurenine pathway.

Fig. 2

A Kynurenic acid (KYNA) was significantly decreased in major depressive disorder subjects that died by suicide (MDD-S) compared to controls (p = 0.011) and decreased compared to MDD subjects that did not die by suicide (MDD-NS) (p = 0.045). B KYAT2 mRNA was significantly increased in MDD-NS compared to controls (p = 0.004). Female subjects are represented by darker colour. Bars indicate mean ± SEM. *p < 0.05, **p < 0.01.