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. 2024 Jan 18;4(1):e0002556. doi: 10.1371/journal.pgph.0002556

Gender differences in adverse childhood experiences, resilience and internet addiction among Tunisian students: Exploring the mediation effect

Imen Mlouki 1,2,3, Mariem Majdoub 2, Emna Hariz 2,*, Ahlem Silini 1,2, Houcem Elomma Mrabet 4, Nejla Rezg 2, Sana El Mhamdi 1,2,3
Editor: Humayun Kabir5
PMCID: PMC10795992  PMID: 38236830

Abstract

Adverse Childhood Experiences (ACEs) are a common public health issue with a variety of consequences, including behavioral addiction such as Internet Addiction (IA). Despite widespread recognition of this issue, the underlying mechanisms are not well studied in recent literature. Additionally, studies have indicated gender disparities in the prevalence and manifestation of ACEs and IA. The objective of this study was to investigate the mediating effect of resilience on the link between ACEs and IA among high-school students according to gender in Mahdia city (Tunisia). We conducted a cross-sectional survey for two months (January- February 2020), among 2520 schooled youth in Mahdia city (Tunisia). The Arabic-language edition of the World Health Organisation ACE questionnaire was used. The validated Arabic versions of the Adolescent Psychological Resilience Scale and the Internet Addiction Test were the screening tools for resilience and IA. Data were analyzed according to gender. The majority of youth (97.5%) were exposed to at least one ACE with the most prevalent being emotional neglect (83.2%). Exposure to extra-familial ACEs was also high reaching 86.9% with higher rates among boys for all types of social violence. Internet addiction was common among students (50%) with higher prevalence for boys (54.4% vs 47.7%for girls, p = 0.006). Resilience scores were86.43 ± 9.7 for girls vs 85.54 ± 9.79 for boys. The current study showed that resilience mediated the link between ACEs, especially intrafamilial violence, and internet addiction (%mediated = 15.1). According to gender, resilience had a significant mediating role on internet addiction for girls (%mediated = 17) and no significant role for boys. The mediating effect of resilience in the relationship between ACEs and cyberaddiction among schooled adolescents in the region of Mahdia (Tunisia) has been identified.

Introduction

Adverse Childhood Experiences (ACEs), which include being subject to physical, mental or sexual violence as well as extra-familial adversities during the first 18 years of life, are connected to a wide range of detrimental health impacts in adolescence and later life [1, 2]. According to recent literature, there are gender disparities concerning childhood maltreatment [3]. ACEs have been linked to a variety types of addiction, not only substance use disorders but also behavioral addictions such as excessive use of internet [4]. According to the World Health Organization (WHO) [5], cyberaddiction is becoming an alarming phenomenon with globally high prevalence rates, predicting an increasing impact with long-lasting psychological and social dangers. In Tunisia, a 2019 survey showed that 43.9% of young students were addicted to internet [6]. Moreover, a Chinese study in 2022, reported that cyberaddiction and mechanisms underlying its associated factors were different according to gender [7].

The mechanism through which ACEs impact teenage behavior have been extensively investigated [2, 8]. However, few studies examined the pathway between ACEs and internet addiction in recent literature [9]. Several regulating virtues have been reported as protective factors against smartphone addiction such as temperance as well as courage [10]. Resilience, broadly defined as the ability of a person to adapt to adverse situations in a positive manner [11, 12], has been recently identified as one of the key protective factors. Indeed, a 2018 study conducted among middle-school youth in Korea revealed the buffering effect of resilience toward internet addiction in girls [13]. Furthermore, research has shown that there is a significant relationship between adverse childhood experiences (ACEs) and resilience, with studies indicating that early life adversities had a negative association with individual resilience [14, 15]. In addition, a recent research carried out in Iran showed that university students with high resilience scores were less prone to substance use despite their vulnerability to addiction [11]. In Slovakia, 2021, it was found that resilience decreased the probability of Emotional and Behavioural Problems (EBP) among adolescents, with documented resilience mediation noted in the relationship between ACE and EBP among teenagers [16]. It was also revealed that resilience played a protective role among psychologically maltreated youngsters in Turkey [17]. Recently, it was found that the gender plays a role in shaping resilience [18]. In Tunisia, a recent ACE survey among youth revealed alarming rates. Indeed, 99.1% reported intra-familial ACEs and 84% expressed being victim of social adversities [2]. Despite these high rates, there is a gap in the Tunisian literature regarding ACEs, let alone ACEs and resilience.

Giving these data and the scarcity of literature in this context, it seems crucial to examine the role of resilience as a contributing element linking ACEs and internet addiction among students in Tunisia in order to establish more efficient and targeted prevention plans among this critical population. Thus, we aimed at assessing the relationship between ACEs and cyberaddiction mediated by resilience among schooled youngsters in Mahdia City, Tunisia.

Methodology

Population study and selection

Participants schooled in all secondary colleges of Mahdia governorate were recruited from January to February 2020. Mahdia is a Tunisian city with a population of 441989 (as at the 2020 census) [19] and a gross enrollment ratio of 94.2% [20].

We randomly selected four classes from each secondary school based on cluster sampling. If we consider a probability of type one error (α) equal to 0.05, a precision of 3% and an internet addiction rate of 43.9% [21], the minimal sample size needed for the current survey is 1052 students.

Inclusion criteria/exclusion

We included all the consented schooled adolescents from Mahdia and Gafsa cities and we excluded students who consent to complete the questionnaire and who did not return it.

A total of 2520 schooled youth were recruited and 1940 returned the questionnaires with an overall response rate of 77%.

Measurement tools

Measurement of adverse childhood experiences

The Adverse childhood experiences-International Questionnaire (ACE-IQ) developed by WHO [8] was used. The Arabic version was validated in Saudi Arabia [22]. The ACE-IQ is intended to measure family dysfunction, physical, sexual and emotional abuse and neglect as well as exposure to bullying, community or collective violence [8]. The ACE score contains nine items (Six items on intrafamilial ACEs and three others on extra familial ACEs). Each item was given a zero or a one point. Thus, the ACE score was marked out of nine.

Evaluation of internet addiction

Cyberaddiction was screened via the validated Arabic version of the Internet Addiction Test (IAT) [23]. Indeed, the internal consistency and the reliability of this scale was excellent (Cronbach alpha coefficient = 0.921). Total IAT scores ranging from 40 to 69 represents over-users with frequent problems caused by their internet use, and scores between 70 and 100 represents cyberaddiction [24]. Thus, the higher the score is, the higher is the level of internet addiction [25].

Measurement of resilience

As defined by the American Psychological Association [26], resilience is the process of adapting well in the face of adversity or significant sources of stress such as relationship problems, serious health problems or workplace and financial stressors. Resilience was measured in the current study using the validated Arabic version of the Adolescent Psychological Resilience Scale [27]. In fact, the exploratory factor analyses of its construct validity explained 56.9% of the total variance and the Cronbach alpha coefficient ranged from 0.61 to 0.89 for its different subscales.

The score assesses six sub-dimensions covering three intrapersonal factors (Adjustment, Sense of struggle, empathy) and three interpersonal factors (Family support, Confidant-friend support, School support). The higher the score is, the higher is the level of resilience [27].

Statistical analysis

Data analyses were performed via SPSS; Version 21. Categorical variables were represented using frequencies and numeric variables were represented using means and standard deviations (SD). To compare percentages and means according to gender, we used the Chi square and the Student tests, respectively. A p-value less than 0.05 was considered statistically significant. ACE, Resilience, Impulsivity and Internet Addiction were considered as quantitative variables. We verified the distribution of these variables, if they followed the normal distribution, the Pearson correlation test was used. If not, Spearman correlation test was used.

Mediation analysis

In this analysis, we examined resilience as a continuous variable to assess its potential role as a mediator. Correlation tests were utilized to determine the zero-order associations between ACEs, resilience and internet addiction. The correlation test was used to check the sign of the correlation coefficient r. If r< 0, the direction of the relationship between the variables is negative. If r> 0, the direction of the relationship between the variables is positive.

Mediation modeling was conducted to ascertain the existence of a significant mediation (or indirect effect) of resilience in the association between ACEs and internet addiction. Resilience was regarded as a potential mediating variable when incorporating it into the model led to a partial or complete reduction of the relationship between ACE as the explanatory variable and internet addiction as the dependent variable [28]. Mediation analyses were carried out utilizing the PROCESS macro created by Andrew F. Hayes [29].

Three major conditions need to be met for mediation analyses. Firstly, the link between the explanatory variable (ACE) and the dependent variable (internet addiction) has to be verified (pathway c). Secondly, the mediation variable (resilience) has to be significantly linked to internet addiction (pathway b). Finally, the link between ACE and resilience must be significant (pathway a). Mediation effect occurs when pathway c is significantly reduced [partial mediation) or no longer significant (full mediation) when the mediator is included into the pathway c (pathway c ′) (Fig 1).

Fig 1. Diagram of the theoretical link between ACE and internet addiction through resilience.

Fig 1

Ethical concerns

The Ethic Committee of Mahdia Teaching Hospital accepted the protocol of the current survey with an approval number of P01 M.P.C- 2020.

The questionnaire was anonymous and self-administered by students. Physicians were in classrooms to elucidate the intent of the survey to students.

The participation was voluntary. In fact, having the writing consent was impossible since the data collection was randomized but informed consent was taken from parents and students before collecting data. In fact, we contacted headmasters before the survey, in order to inform parents and students in schools.

Results

General characteristics of schooled youngsters in Mahdia city

A total of 1940 returned the questionnaires with a mean age of 17 ±1.5. Girls represented of the majority of the study sample (66.3%). At the first level of education, men were more prevalent than women (32% vs. 27.6%, p 0.01). The fourth level, however, had a higher percentage of girls (25.7% as opposed to 20.5%).

Distribution of ACEs by gender within and outside of families

Table 1 presents the breakdown of all categories of ACEs. In fact, intra-familial ACEs (94.5%) were more reported by students than social ACEs (86.9%). Boys were significantly more exposed to physical abuse and all types of social ACEs than girls (Table 1).

Table 1. Prevalence of ACEs among students by gender.

Categories of ACEs, n (%) Total (n = 1940) Boy (n = 662) Girl(n = 1278) p value
Intra-familial ACEs 1786 (94.5) 608 (95.8) 1178 (93.9) 0.2
Emotional neglect 1601 (83.2) 538 (83.8) 1057 (83.1) 0.6
Household dysfunction 1534 (80.5) 499 (78.5) 1030 (81.7) 0.09
Physical abuse 1082 (56.3) 391 (61) 687 (54.1) 0.004
Emotional abuse 594 (30.8) 197 (30.6) 394 (31) 0.8
Physical neglect 469 (24.4) 173 (26.9) 293 (23.1) 0.06
Sexual abuse 257 (13.4) 93 (14.5) 162 (12.8) 0.2
Social ACEs 1648 (86.9) 589 (92.5) 1059 (84) <0.0001
Community violence 1417 (73.5) 541 (84) 870 (68.3) <0.0001
Peer violence 1224 (64.1) 437 (68.5) 784 (62.1) 0.006
Collective violence 359 (18.6) 188 (29.2) 169 (13.3) <0.0001

Resilience score results and internet addiction prevalence among students by gender

Table 2 summarizes the total score of the adolescent psychological resilience scale as well as scores on its six sub-dimensions by gender. Resilience scores were moderate to high among questioned students with a higher total resilience score among girls. Regarding sub-dimension scores, girls had a significantly higher score for school support (15.53 ±3.63 vs 14.84 ±3.7, p<0.001) (Table 2).

Table 2. Resilience scores among schooled youngsters by gender (n = 1887).

Characteristics Boy (n = 634) Girl (n = 1253) p value
Total resilience score (min = 50, max = 109) 85.54 ± 9.79 86.43 ± 9.7 0.063
Sub-dimension scores
Family support 22.43 ± 4.18 22.72 ± 4.43 0.16
Confidant / Friend support 15.73 ± 3.84 15.64 ± 4.12 0.66
School support 14.84 ± 3.7 15.53 ± 3.63 <0.0001
Adjustment 10.3 ± 2.35 10.16 ± 2.31 0.22
Sense of struggle 13.06 ± 2.08 13.05 ± 2.16 0.91
Empathy 9.24 ± 2.23 9.33 ± 2.15 0.36

Fifty percent of youth had cyberaddiction in our sample. Boys were more likely to be addicted than girls (54.4% vs 47.7%, p< 0.006).

Resilience as a mediator between ACEs and internet addiction among students

Every variable incorporated in the mediation analysis displayed significant correlations. (Table 3). The total count of ACEs (pathway c) and Resilience (pathway b) were independently linked with Internet addiction (p<0.001), and ACEs were significantly linked with Resilience (pathway a) (p <0.001);the number of total ACEs and resilience were inversely correlated (p< 0.001, r = -0.34) (when the number of total ACEs increased, resilience decreased), oppositely, total ACEs and IA score were positively correlated (p< 0.001, r = 0.30) (when the number of ACEs increased, IA increased). Besides, we found that Resilience and IA scores were negatively correlated (p< 0.001, r = -0.19) (when resilience decreased, IA increased).

Table 3. Zero-order relationships between ACE, resilience and internet addiction among students.

(1) (2)
Number of total ACEs -0.34*** 0.30***
(1) Resilience -0.19***
(2) Internet addiction
Number of intrafamilial ACEs -0.32*** 0.25***
Number of extrafamilial ACEs -0.25*** 0.27***

***: p < 0.001

The total count of all ACEs, which served as the exposure variable, and internet addiction, which served as the outcome variable, both showed statistically significant partial mediation effects of resilience (p< 0.001, % mediated = 10.3%) (Pathway c’). In fact, resilience contributes by 10.3% as a protective factor in the link between ACEs and IA.

Resilience was found to partially mediate the impact of both intra-familial ACEs and extra-familial ACEs. Intra-familial ACEs exhibited a higher degree of mediation by Resilience, accounting for 15.1% of the effect (p < 0.001), whereas exposure to extra-familial ACEs showed a slightly lower mediation effect at 10.1% (p <0.001) (Pathway c’) (Table 4).

Table 4. Mediation model of the relationship of ACE’s types on internet addiction with resilience as a mediator among youth (N = 1830).

Coefficients* Sobel test % Mediated
Mediator a b C c’ SE P
Type of ACEs:
Total ACEs -1.72 -0.21 3.41 3.05 0.09 <0.001 10.3
Intra-familial ACEs -2.26 -0.27 3.95 3.33 0.12 <0.001 15.1
Social ACEs -2.69 -0.28 6.79 6.03 0.15 <0.001 10.1

┼ % Mediated = c–c’/c, ╪Mediator: Resilience Adjusted to gender and age

According to gender (Table 5), Among girls, there were noteworthy interactions observed between childhood adversities and resilience in relation to internet addiction (p < 0.001; % mediation = 17%). However, for boys, no statistically significant indirect effect was detected for ACEs in their association with internet addiction through resilience (p = 0.83; % mediation = 0.08%) (Table 5).

Table 5. The association between ACEs and internet addiction through resilience among students according to gender.

Coefficients* Sobel test % Mediated
Mediator a b c c’ SE p
Mediation model for girls (N = 1216)
Total ACEs -1.79 -0.30 3.27 2.71 0.12 <0.001 17%
Mediation model for boys (N = 607)
Total ACEs -1.59 -0.01 3.47 3.44 0.14 0.83 0.08%

┼ % Mediated = c–c’/c

╪Mediator: Resilience

Discussion

Our survey clearly highlights the mediating role of resilience between ACEs, especially intrafamilial violence and internet addiction among students in Mahdia city (% mediation = 15.1). According to gender, we found higher mediation part among girls (p <0.001; % mediation = 17). However, no significant indirect effect was found between ACEs and cyberaddiction through resilience among boys (p = 0.83; % mediation = 0.08%). To the best of our understanding, this is the initial survey in the Middle-East and North Africa region that explores this pathway.

The studied sample counted 1940 schooled adolescents of which girls represented 66.3%. We observed that while boys were more widespread than girls at the initial educational stage, they were less common in the fourth tier. This difference may be clarified by social and economic factors leading to higher drop-out rates for male adolescents. Our results are not consistent with those reported in a Malysian review [30]. This might be related to our retrospective data collection. In view of the scarcity of Tunisian literature about drop-out among youth, a prospective national study will be useful to explore this phenomenon.

We found that 94.5% and 87% of schooled adolescents reported experiencing intrafamilial and social adversities respectively. These frequencies are high compared to other developing non-westernized countries, for example a research in china showed50% of exposure to ACEs [31]. Similar rate(52.6%) was reported by youth in eight European countries including Albania, Latvia, Lithuania, Montenegro, Romania, the Russian Federation, North Macedonia, and Turkey [32]. Our results are closer, while still higher, to those found in Saudi Arabia (81.7%) [22] and in Vietnam (76.2%) [33]. A Tunisian study showed that exposure to intra-familial violence was more reported than social adversities with 99.1% and 84% respectively [34]. Thus, these alarming rates call for urgent measures to be taken in order to mitigate leading factors to ACEs.

Based on our findings, the most reported intrafamilial violence among youth was being emotionally neglected (83.2%) succeeded by household dysfunction (80.5%) with no gender difference. The ranking is aligned with western results despite an important difference between rates. For instance, a Japanese study among students revealed that the highest intra-familial ACEs were household dysfunction (13.8%) and emotional abuse (13.7%) with a higher prevalence among girls (16% vs 11.6%) [35]. Similarly, female adolescents in the United Kingdom were more exposed to emotional abuse (8% vs 5.5%) [36]. These differences may be explained by social and cultural determinants. Another strikingly high rate is that 13.4% of students reported being sexually abused with no gender difference. It is important to note that this percentage may be underestimated due to disclosure problems and socio-cultural factors. According to a recent meta-analysis, the global rate of child sexual abuse is around 7% for boys and 19% for girls [37]. In our sample, the rate for boys (14.5%) is double the global rate while the rate for girls is relatively lower. Our findings are concordant with those reported in Croatia (10.8%) [38] and Saudi Arabia(14%) [39]. This substantial contrast between rates might be related to the dissimilarity in measurement instruments as well as the scarcity in data especially in conservative countries. Indeed, conducting studies at a broader scale and taking immediate actions to prevent this alarming phenomenon are needed. According to the Center for Disease Control, ACEs primary prevention is based on strengthening household financial security, establishing “family-friendly work policies” and connecting youth to caring adults and activities” in after-school programs [40].

Regarding social violence, being victim of bullying was common (64.1%) among questioned adolescents. This prevalence is significantly higher compared to rates observed in the United States (41.2%) [41] and in Arabic countries such as Algeria (38.3%) and Lebanon (25.1%) [42]. More particularly, cyberbullying is a growing worldwide concern related to the growing use of social networks applications especially among youth. In our sample, 33.4% of schooled adolescents reported being victims of cyberbullying. The Global Kids online study [43] revealed similar cyberbullying rates in Bulgaria (38%) and in Chile (36%) whereas rates were significantly higher in Uruguay (56%) and in Italy (48%). A survey conducted among young people in 42 countries about Social Media Use (SMU) showed that cyberbullying victimization was higher for girls (17.2% vs 13.9%) [44]. This highlights the negative facet of unsupervised and uneducated internet use among adolescents. In fact, it was demonstrated that cyberbullying lead to several mental health issue including depression, borderline personality disorder, sleep deprivation and suicidal thoughts [45]. A global approache in forcing protective behaviors among youth but also supervising online content is required by collaborating with technology sponsors, social actors and educational staff [46]. In addition, it is advisable to take in charge victims early with clear instructions and guidance.

One of the key observations in our study is the prevalence of internet addiction (50%) with a higher prevalence among boys. Our finding is consistent with a 2019 Tunisian survey [6] showing that 49.9% of students were addicted. These rates are extremely high compared to those shown by a meta-analysis including 30 studies from Europe, Asia, America and Oceania and estimating an overall addiction prevalence of 24.6% among youth [47]. It is important to note that these risky behaviors suspected to be accentuated during the COVID-19 outbreak. Indeed, cyberaddiction rate among students climbs from 11.69% [48] to 24.4% [49] after the pandemic in Taiwan. Interned addiction is recognized to have both immediate and long-term consequences such as sleep disorders [50], social isolation [51], active violence especially amongst boys and suicidal ideation [38, 52].

To face the widespread of internet addiction and its harmful side effects among youth, it is also useful to investigate mediators that help preventing this risky behavior. According to a recent meta-analysis [53], intrapersonal determinants (self-identity, self-control, emotional regulation..) had higher protective effect than interpersonal variables (relational ability, family relationship..). In our study, we evaluated resilience among schooled adolescents based on both intrapersonal factors covering adjustment, sense of struggle as well as empathy and interpersonal factors including family support, friend support and school support. We found that resilience scores were moderate to high among youth with a score of 86.43 ± 9.7 for girls vs 85.54 ± 9.79 for boys. Our findings are in line with those reported among adolescents in Iran(84.41±11.01) and in Poland (67.66 ±15.15) [54, 55]. Gender disparity was identified in both studies: In Iran, the resilience level was significantly higher among girls. However, girls had significantly lower levels in Poland [54, 55].

Our research reveals the significant mediating effect of resilience in the link between exposure to ACEs and internet addiction among adolescents (% mediated = 10.3). Regarding the association between ACEs and resilience, a2022 study [56] showed similar results. In fact, cumulative ACE exposure was associated with lower resilience among adult women in Iceland [56]. Concerning the relationship between resilience and internet addiction, several western studies investigated this link. However, few data were available in developing countries and we were unable to compare our results. Our finding is in agreement with a recent study examining the protective role of resilience [57] and showing that higher resilience score was associated with lower internet addiction level. Added to that, it was proven in China that enhancing children resilience can be an effective way to reduce cyberaddiction [58]. According to gender, this mediation was only significant for girls (%mediated = 17). Our interesting result is concordant with a Korean survey [13] concluding that, although there was no significant sex difference in resilience, the buffering effect of resilience toward internet addiction only emerged in girls. This fact may be inferred by the difference in goals and motivation for internet use between boys and girls. Indeed, it was reported that boys are more likely to use the internet for pleasure [4] by engaging in online gaming or cybersexual activities [52] whereas girls are more likely to use internet to seek information and engage in social networking [59]. Thus, a potential explanation to the major mediation effect of resilience for girls, is that benefiting from stronger interpersonal resilience factors (Family support, friend support, school support) can balance the primary motivation of girls for internet use (information seeking and social networking) and hence reduce the risk of internet addiction [13]. However, this mediating effect is more limited for boys who have predominantly different motivation.

These results emphasize the importance of implementing effective measures to reinforce resilience by targeting both intrapersonal and interpersonal factors. It is compulsory to promote safe home environment by addressing issues such as neglect and household dysfunction. Providing access to mental support systems and involving extracurricular activities that raise awareness about ACEs as well as the protective role of resilience are needed [6062]. These recommendations should be adapted to fit the resources of low-income communities.

The current study has some limitations. First, the cross-sectional nature of data collection did not provide an understanding of the temporal association between adverse experiences, resilience, and internet addiction. Second, cyberaddiction was evaluated globally, with no type specification (gaming, social media, information seeking). Consequently, additional future studies using targeted measurement tools are needed to better determine protective and risk factors. Third, the present survey was carried out in a single Tunisian governorate, which limits the representativeness of our findings. In addition, the rate of cyberaddiction among students has recently increased after thecovid-19 pandemic [49]. Thus, reported rates in our research are probably underestimated. Evaluating the impact of covid-19 outbreak on risky behaviors is need. Fourthly, we notice that the resilience scale is too long and contains similar items that maybe confusing for the respondent. However, to the best of our knowledge, it was the only available validated Arabic tool for screening resilience. Finally, in the mediation model, we have not adjusted for confounding variables such as depression and anxiety. Future studies need to consider these variables.

Conclusion

Our study is among the initial ones in Tunisia to investigate the mediating role of resilience in the association between ACEs and cyberaddiction in the adolescent population. Specifically, we found a major contribution of resilience between intra-familial ACEs and internet addiction for girls (%mediation = 17) with no significant indirect effect for boys. This opens the door to child and adolescent psychiatrists to explore this pathway and urgently implement effective preventive strategy based on developing life skills and promoting safe use of internet among youth in Tunisia.

Supporting information

S1 Data. Adverse childhood experiences, resilience and internet addiction.

(SAV)

S2 Data. The full list of legends for the supporting information file.

(DOCX)

Acknowledgments

The authors are grateful to the following people for their help in data collection: Faouzia Chebbi, Sarra Nouira, Ines Daldoul Chebbi, Fethi Aroui and Asma Sayadi. We seize this opportunity to express our gratitude to all the team of The Epidemiology and Preventive Medicine Department at the University Hospital Taher Sfar Mahdia.

Data Availability

The data used to support the findings of the study are available in the supporting information file.

Funding Statement

The authors received no specific funding for this work.

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PLOS Glob Public Health. doi: 10.1371/journal.pgph.0002556.r001

Decision Letter 0

Humayun Kabir

12 Sep 2023

PGPH-D-23-01242

Gender differences in adverse childhood experiences, resilience and internet addiction among Tunisian students: Exploring the mediation effect.

PLOS Global Public Health

Dear Dr. Hariz,

Thank you for submitting your manuscript to PLOS Global Public Health. After careful consideration, we feel that it has merit but does not fully meet PLOS Global Public Health’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by October 01, 2023. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at globalpubhealth@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pgph/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

We look forward to receiving your revised manuscript.

Kind regards,

Humayun Kabir

Academic Editor

PLOS Global Public Health

Journal Requirements:

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a. State what role the funders took in the study. If the funders had no role in your study, please state: “The funders had no role in study design, data collection and analysis, decision to publish, or preparation of the manuscript.”

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If you did not receive any funding for this study, please simply state: “The authors received no specific funding for this work.”

PGPH-D-23-01242

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2. We noticed you have some minor occurrence of overlapping text with the following previous publication(s), which needs to be addressed:

- https://www.sciencedirect.com/science/article/pii/S2211335521001145?via%3Dihub

3. In your revision ensure you cite all your sources (including your own works), and quote or rephrase any duplicated text outside the methods section. Further consideration is dependent on these concerns being addressed.""

4. Please provide additional details regarding participant consent. In the ethics statement in the Methods and online submission information, please ensure that you have specified (1) whether consent was informed and (2) what type you obtained (for instance, written or verbal, and if verbal, how it was documented and witnessed). If your study included minors, state whether you obtained consent from parents or guardians. If the need for consent was waived by the ethics committee, please include this information.

5. If you are reporting a retrospective study of medical records or archived samples, please ensure that you have discussed whether all data were fully anonymized before you accessed them and/or whether the IRB or ethics committee waived the requirement for informed consent. If patients provided informed written consent to have data from their medical records used in research, please include this information.

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This policy applies to all data except where public deposition would breach compliance with the protocol approved by your research ethics board. If your data cannot be made publicly available for ethical or legal reasons (e.g., public availability would compromise patient privacy), please explain your reasons by return email and your exemption request will be escalated to the editor for approval. Your exemption request will be handled independently and will not hold up the peer review process, but will need to be resolved should your manuscript be accepted for publication. One of the Editorial team will then be in touch if there are any issues.

Additional Editor Comments (if provided):

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. Does this manuscript meet PLOS Global Public Health’s publication criteria? Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe methodologically and ethically rigorous research with conclusions that are appropriately drawn based on the data presented.

Reviewer #1: Partly

Reviewer #2: Yes

Reviewer #3: Yes

Reviewer #4: Yes

**********

2. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: No

Reviewer #2: Yes

Reviewer #3: No

Reviewer #4: No

**********

3. Have the authors made all data underlying the findings in their manuscript fully available (please refer to the Data Availability Statement at the start of the manuscript PDF file)?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception. The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: No

Reviewer #2: Yes

Reviewer #3: No

Reviewer #4: No

**********

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Reviewer #1: Yes

Reviewer #2: Yes

Reviewer #3: No

Reviewer #4: Yes

**********

5. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: This manuscript examined the mediating role of resilience in the association between adverse childhood experiences and internet addiction among Tunisian youth. The topic is important and the study has some promise, but there are some major methodological issues that must be considered before any useful conclusions can be made. My specific comments are below

-Introduction: This section does not provide justification for considering resilience as a mediator in the association between ACEs and internet addiction. The cited studies support the role of resilience as a moderator (effect modifier) rather than a mediator. By definition, a mediating variable must be on the causal pathway between the exposure and the outcome. Are there studies that support a causal relationship between ACEs and resilience?

-Methods: This section is significantly lacking in details throughout. More information is needed regarding the study sample (how many were recruited, how many consented, response rate), measurement (how were the main variables used in the analysis?), and statistical methods (see below)

-Statistical methods: No details were provided on the methods used to examine the associations. The authors mention adding the mediator to a model without providing any further details regarding the modeling procedures used.

-How were the numbers in Table 3 obtained?

-In the methods section, there was no mention of adjusting for confounding variables. This is a serious flaw in this manuscript that was not even mentioned in the limitations section.

-Results: In table 4, the coefficients include c' which was not mentioned elsewhere. What is this pathway and how was it obtained?

-In the interpretation of results, the authors make no mention of the direction of the associations and the implications of these directions on the mediation results.

-Discussion: Most of this section is focused on the descriptive results and comparing them to the literature, rather than results that answer the research question (mediation).

-In the discussion, the author's interpretation of the results and their implications is more appropriate for a moderator/effect modifier rather than a mediator. The literature cited in the discussion also supports the role of resilience as a moderator, which would have been a better approach for this analysis than mediation.

-The main limitation, acknowledged by the authors, is the cross-sectional design which does not permit the determination of temporality. This limitation violates the basic assumptions required for mediation analysis, which is another reason why mediation was inappropriate in this case.

Reviewer #2: I enjoyed reading about your research and particularly liked the comparative inclusion of data from multiple countries. I would have liked to see the role of ACE and Resilience on overall behavioral addiction mentioned. I assume you find resilience more significant for males in general addiction or other behavioral addictions. Great work.

Reviewer #3: Information in the abstract does not match with the title, especially the gender difference. Please modify the introduction and method sections of the abstract.

Data should be available online as per plos policy.

Please improve the justification of the study.

Add why this study is needed in the context of the country as similar studies are already published.

Follow the reporting guidelines STOBE and cover all the sections in the STOBE.

Give description of the population.

Add a section for the questionnaire development.

Add a section for the data collection techniques.

Add a section for the bias.

Add a sections for the dependent variables and independent variables.

Add the exclusion and inclusion criteria.

Report the sampling techniques.

Report the sample size calculation.

Repot the validity and reliability of the tools used in this study.

Reviewer #4: “Qualitative variables were

134 represented by absolute and relative frequencies and quantitative ones were represented by

135 means and standard deviations (SD)” why qualitative variables? Is it a mix method study? If so, how can it be express in frequencies?

“To compare percentages and means, we used the Chi

136 square and the Student tests, respectively” mention why and when this test were done and the purpose of the tests.

The gender is covered male and female that is basically sex. Why not author say it sex difference?

The justification of the sex difference should be mentioned in the justification of the introduction.

Report the limitation of the study.

Mention what is new in this study in a section.

Give a recommendation.

What are the further research in needed, add a section for that.

**********

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For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: No

Reviewer #3: No

Reviewer #4: No

**********

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

While revising your submission, please upload your figure files to the Preflight Analysis and Conversion Engine (PACE) digital diagnostic tool, https://pacev2.apexcovantage.com/. PACE helps ensure that figures meet PLOS requirements. To use PACE, you must first register as a user. Registration is free. Then, login and navigate to the UPLOAD tab, where you will find detailed instructions on how to use the tool. If you encounter any issues or have any questions when using PACE, please email PLOS at figures@plos.org. Please note that Supporting Information files do not need this step.

PLOS Glob Public Health. doi: 10.1371/journal.pgph.0002556.r003

Decision Letter 1

Humayun Kabir

7 Nov 2023

PGPH-D-23-01242R1

Gender differences in adverse childhood experiences, resilience and internet addiction among Tunisian students: Exploring the mediation effect.

PLOS Global Public Health

Dear Dr. Hariz,

Thank you for submitting your manuscript to PLOS Global Public Health. After careful consideration, we feel that it has merit but does not fully meet PLOS Global Public Health’s publication criteria as it currently stands. Therefore, we invite you to submit a revised version of the manuscript that addresses the points raised during the review process.

Please submit your revised manuscript by December 2, 2023. If you will need more time than this to complete your revisions, please reply to this message or contact the journal office at globalpubhealth@plos.org. When you're ready to submit your revision, log on to https://www.editorialmanager.com/pgph/ and select the 'Submissions Needing Revision' folder to locate your manuscript file.

Please include the following items when submitting your revised manuscript:

  • A rebuttal letter that responds to each point raised by the editor and reviewer(s). You should upload this letter as a separate file labeled 'Response to Reviewers'.

  • A marked-up copy of your manuscript that highlights changes made to the original version. You should upload this as a separate file labeled 'Revised Manuscript with Track Changes'.

  • An unmarked version of your revised paper without tracked changes. You should upload this as a separate file labeled 'Manuscript'.

Guidelines for resubmitting your figure files are available below the reviewer comments at the end of this letter.

We look forward to receiving your revised manuscript.

Kind regards,

Humayun Kabir

Academic Editor

PLOS Global Public Health

Journal Requirements:

1. We noticed you have some minor occurrence of overlapping text with the following previous publication(s), which needs to be addressed:

- https://www.sciencedirect.com/science/article/pii/S2211335521001145?via%3Dihub

In your revision ensure you cite all your sources (including your own works), and quote or rephrase any duplicated text outside the methods section. Further consideration is dependent on these concerns being addressed.""

2. Please provide additional details regarding participant consent. In the ethics statement in the Methods and online submission information, please ensure that you have specified (1) whether consent was informed and (2) what type you obtained (for instance, written or verbal, and if verbal, how it was documented and witnessed). If your study included minors, state whether you obtained consent from parents or guardians. If the need for consent was waived by the ethics committee, please include this information.

If you are reporting a retrospective study of medical records or archived samples, please ensure that you have discussed whether all data were fully anonymized before you accessed them and/or whether the IRB or ethics committee waived the requirement for informed consent. If patients provided informed written consent to have data from their medical records used in research, please include this information.

Please review your reference list to ensure that it is complete and correct. If you have cited papers that have been retracted, please include the rationale for doing so in the manuscript text, or remove these references and replace them with relevant current references. Any changes to the reference list should be mentioned in the rebuttal letter that accompanies your revised manuscript. If you need to cite a retracted article, indicate the article’s retracted status in the References list and also include a citation and full reference for the retraction notice.

Additional Editor Comments (if provided):

[Note: HTML markup is below. Please do not edit.]

Reviewers' comments:

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #1: (No Response)

Reviewer #2: All comments have been addressed

**********

2. Does this manuscript meet PLOS Global Public Health’s publication criteria? Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe methodologically and ethically rigorous research with conclusions that are appropriately drawn based on the data presented.

Reviewer #1: (No Response)

Reviewer #2: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: (No Response)

Reviewer #2: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available (please refer to the Data Availability Statement at the start of the manuscript PDF file)?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception. The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: (No Response)

Reviewer #2: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS Global Public Health does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: (No Response)

Reviewer #2: Yes

**********

6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: Thank you for addressing my comments. The manuscript has improved significantly.

The only issue that was not corrected is the lack of adjustment for confounders. I was hoping the authors would use regression analysis to control for confounders such as socioeconomic status (parental income or education), family structure (2 parents vs. single parent, number of siblings), anxiety or depression, in addition to age and sex.

Are these variables available in the survey? If one or more variable is available, I recommend using regression analysis to control for measured confounders.

Reviewer #2: Thank you for your response. I hope to see more research done later about this matter

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Do you want your identity to be public for this peer review? If you choose “no”, your identity will remain anonymous but your review may still be made public.

For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: No

**********

[NOTE: If reviewer comments were submitted as an attachment file, they will be attached to this email and accessible via the submission site. Please log into your account, locate the manuscript record, and check for the action link "View Attachments". If this link does not appear, there are no attachment files.]

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PLOS Glob Public Health. doi: 10.1371/journal.pgph.0002556.r005

Decision Letter 2

Humayun Kabir

18 Dec 2023

Gender differences in adverse childhood experiences, resilience and internet addiction among Tunisian students: Exploring the mediation effect.

PGPH-D-23-01242R2

Dear Hariz,

We are pleased to inform you that your manuscript 'Gender differences in adverse childhood experiences, resilience and internet addiction among Tunisian students: Exploring the mediation effect.' has been provisionally accepted for publication in PLOS Global Public Health.

Before your manuscript can be formally accepted you will need to complete some formatting changes, which you will receive in a follow up email. A member of our team will be in touch with a set of requests.

Please note that your manuscript will not be scheduled for publication until you have made the required changes, so a swift response is appreciated.

IMPORTANT: The editorial review process is now complete. PLOS will only permit corrections to spelling, formatting or significant scientific errors from this point onwards. Requests for major changes, or any which affect the scientific understanding of your work, will cause delays to the publication date of your manuscript.

If your institution or institutions have a press office, please notify them about your upcoming paper to help maximize its impact. If they'll be preparing press materials, please inform our press team as soon as possible -- no later than 48 hours after receiving the formal acceptance. Your manuscript will remain under strict press embargo until 2 pm Eastern Time on the date of publication. For more information, please contact globalpubhealth@plos.org.

Thank you again for supporting Open Access publishing; we are looking forward to publishing your work in PLOS Global Public Health.

Best regards,

Humayun Kabir

Academic Editor

PLOS Global Public Health

***********************************************************

Reviewer Comments (if any, and for reference):

Reviewer's Responses to Questions

Comments to the Author

1. If the authors have adequately addressed your comments raised in a previous round of review and you feel that this manuscript is now acceptable for publication, you may indicate that here to bypass the “Comments to the Author” section, enter your conflict of interest statement in the “Confidential to Editor” section, and submit your "Accept" recommendation.

Reviewer #1: All comments have been addressed

Reviewer #2: All comments have been addressed

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2. Does this manuscript meet PLOS Global Public Health’s publication criteria? Is the manuscript technically sound, and do the data support the conclusions? The manuscript must describe methodologically and ethically rigorous research with conclusions that are appropriately drawn based on the data presented.

Reviewer #1: Yes

Reviewer #2: Yes

**********

3. Has the statistical analysis been performed appropriately and rigorously?

Reviewer #1: Yes

Reviewer #2: Yes

**********

4. Have the authors made all data underlying the findings in their manuscript fully available (please refer to the Data Availability Statement at the start of the manuscript PDF file)?

The PLOS Data policy requires authors to make all data underlying the findings described in their manuscript fully available without restriction, with rare exception. The data should be provided as part of the manuscript or its supporting information, or deposited to a public repository. For example, in addition to summary statistics, the data points behind means, medians and variance measures should be available. If there are restrictions on publicly sharing data—e.g. participant privacy or use of data from a third party—those must be specified.

Reviewer #1: Yes

Reviewer #2: Yes

**********

5. Is the manuscript presented in an intelligible fashion and written in standard English?

PLOS Global Public Health does not copyedit accepted manuscripts, so the language in submitted articles must be clear, correct, and unambiguous. Any typographical or grammatical errors should be corrected at revision, so please note any specific errors here.

Reviewer #1: Yes

Reviewer #2: Yes

**********

6. Review Comments to the Author

Please use the space provided to explain your answers to the questions above. You may also include additional comments for the author, including concerns about dual publication, research ethics, or publication ethics. (Please upload your review as an attachment if it exceeds 20,000 characters)

Reviewer #1: Thank you for addressing my concerns. I have no further comments

Reviewer #2: N/A

**********

7. PLOS authors have the option to publish the peer review history of their article (what does this mean?). If published, this will include your full peer review and any attached files.

Do you want your identity to be public for this peer review? If you choose “no”, your identity will remain anonymous but your review may still be made public.

For information about this choice, including consent withdrawal, please see our Privacy Policy.

Reviewer #1: No

Reviewer #2: No

**********

Associated Data

    This section collects any data citations, data availability statements, or supplementary materials included in this article.

    Supplementary Materials

    S1 Data. Adverse childhood experiences, resilience and internet addiction.

    (SAV)

    S2 Data. The full list of legends for the supporting information file.

    (DOCX)

    Attachment

    Submitted filename: Response to reviewers.docx

    Attachment

    Submitted filename: Response to reviewers.docx

    Data Availability Statement

    The data used to support the findings of the study are available in the supporting information file.


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