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. 2023 Dec 7;25(1):165–167. doi: 10.1007/s40257-023-00825-0

Author Correction: Efficacy and Safety of Apremilast for the Treatment of Japanese Patients with Palmoplantar Pustulosis: Results from a Phase 2, Randomized, Placebo-Controlled Study

Tadashi Terui 1,, Yukari Okubo 2, Satomi Kobayashi 3, Shigetoshi Sano 4, Akimichi Morita 5, Shinichi Imafuku 6, Yayoi Tada 7, Masatoshi Abe 8, Masafumi Yaguchi 9, Natsuka Uehara 9, Takahiro Handa 9, Masayuki Tanaka 9, Wendy Zhang 10, Maria Paris 10, Masamoto Murakami 11
PMCID: PMC10796414  PMID: 38060175

Author Correction: American Journal of Clinical Dermatology (2023) 24:837-847 10.1007/s40257-023-00788-2

Page 840, Table 1 Baseline Patient Demographics and Clinical Characteristics

(ITT Population):

‘PPPASI score categories at randomization, n (%)’ section, ‘≤ 20’ row: The cell entry in the ‘Placebo’ column, which previously read:

“15 (34.1)”

should read:

"14 (31.8)”

‘PPPASI score categories at randomization, n (%)’ section, ‘≥ 21 to ≤ 30’ row: The cell entry in the ‘Placebo’ column, which previously read:

“18 (40.9)”

should read:

“19 (43.2)”

‘Focal infection status at randomization, n (%)’ section, ‘Presence’ row: The cell entry in the ‘Placebo’ column, which previously read:

“34 (77.3)”

should read:

“32 (72.7)”

‘Focal infection status at randomization, n (%)’ section, ‘Absence’ row: The cell entry in the ‘Placebo’ column, which previously read:

“10 (22.7)”

should read:

“12 (27.3)”

‘Focal infection status at randomization, n (%)’ section, 'Presence' row: The cell entry in the ‘Apremilast 30 mg BID’ column, which previously read:

“37 (80.4)”

should read:

“32 (69.6)”

‘Focal infection status at randomization, n (%)’ section, 'Absence' row: The cell entry in the ‘Apremilast 30 mg BID’ column, which previously read:

“9 (19.6)”

should read:

“14 (30.4)”

The corrected Table 1 is as follows:

Table 1.

Baseline patient demographics and clinical characteristics (ITT population)

Placebo (n = 44) Apremilast 30 mg BID (n = 46)
Age, years
 N 44 46
 Mean (SD) 54.7 (11.68) 54.9 (11.30)
Sex, n (%)
 Male 11 (25.0) 10 (21.7)
 Female 33 (75.0) 36 (78.3)
BMI, kg/m2
 N 44 46
 Mean (SD) 25.33 (5.309) 24.37 (3.732)
Tobacco use, n (%)
 User 38 (86.4) 37 (80.4)
 Non-user 6 (13.6) 9 (19.6)
Duration of PPP, years
 N 44 46
 Mean (SD) 7.53 (9.026) 7.34 (8.627)
PPPASI score categories at randomization, n (%)
 ≤ 20 14 (31.8) 16 (34.8)
 ≥ 21 to ≤ 30 19 (43.2) 18 (39.1)
 ≥ 31 11 (25.0) 12 (26.1)
PPSI total score
 N 44 46
 Mean (SD) 8.2 (1.5) 8.3 (1.5)
PGA, n (%)
 2 1 (2.3) 3 (6.5)
 3 24 (54.5) 16 (34.8)
 4 17 (38.6) 21 (45.7)
 5 2 (4.5) 6 (13.0)
Pruritus VAS
 N 42 46
 Mean (SD) 57.0 (27.8) 50.3 (31.6)
Pain VAS
 N 42 46
 Mean (SD) 50.3 (30.0) 45.4 (31.9)
DLQI total score
 N 43 46
 Mean (SD) 7.2 (4.7) 7.5 (4.9)
Focal infection status at randomization, n (%)
 Presence 32 (72.7) 32 (69.6)
 Absence 12 (27.3) 14 (30.4)

APR apremilast 30 mg twice daily, BMI body mass index, PBO placebo, PPP palmoplantar pustulosis, PPPASI Palmoplantar Pustular Area and Severity Index, SD standard deviation

Page 841, Fig. 1 legend:

The footnote that previously read:

“*Two-sided P-value (nominal) is based on chi-square test. Missing data were imputed by nonresponder imputation.”

should read:

“*Two-sided P-value is based on chi-square test. Missing data were imputed by nonresponder imputation.”

Page 841, Fig. 1:

The text above the PPPASI-50 columns that previously read:

“Treatment difference: 37.4% (95% CI: 18.6%, 56.1%) Nominal P=0.0003*”

should read:

“Treatment difference: 37.4% (95% CI: 18.6%, 56.1%) P=0.0003*”

The original article has been corrected.


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