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The Cochrane Database of Systematic Reviews logoLink to The Cochrane Database of Systematic Reviews
. 1998 Oct 26;1998(4):CD000473. doi: 10.1002/14651858.CD000473.pub2

Interventions for chronic suppurative otitis media

Jose M Acuin 1,, Andrew Smith 2, Ian Mackenzie 3
Editor: Cochrane ENT Group
PMCID: PMC10798418  PMID: 17636638

Reason for withdrawal from publication

24/08/05 Withdrawn from The Cochrane Library

This review is to be replaced by 7 separate reviews:

1. Aural toilet: aural toilet versus no treatment or various methods of aural toilet 
 2. Systemic antibiotic treatment: systemic antibiotics versus no treatment or aural toilet, or various methods of systemic antibiotics 
 3. Topical antiseptics: topical antiseptic versus no treatment or aural toilet, or various topical antiseptics 
 4. Topical antibiotics without steroids: topical antibiotic, versus no treatment or aural toilet, topical antiseptics or various topical antibiotics, excluding steroids 
 5. Systemic versus topical treatments: any systemic treatment against any topical treatment excluding steroids 
 6. Systemic or topical steroids: steroids, as monotherapy or combination therapy, versus no treatment or aural toilet, topical antiseptics, topical antibiotics, or systemic antibiotics 
 7. Surgical treatment: surgery versus no treatment or any other treatment

The editorial group responsible for this previously published document have withdrawn it from publication.

Keywords: Humans; Chronic Disease; Otitis Media, Suppurative; Otitis Media, Suppurative/therapy

Feedback

Arroll 2000

Summary

I am an author of the common cold and antibiotics review. I have recently been reviewing the Cochrane review of chronic suppurative otitis media. I have two points I would like to make to the authors. First I feel their comment that topical antibiotics with aural toilet is the most effective means of treatment. This is contrary to their own data which shows that aural toilet + antibiotics is better than aural toilet. This would suggest to me that it is the topical antibiotics which are being effective here. Also the comparison antibiotics versus antiseptics includes papers by Esposito 1990, Esposito 1992 and Povendano 1995. None of these papers includes a topical antiseptic.

The MetaView comparison of antibiotic/antiseptic versus systemic antibiotics with an outcome of positive culture includes 3 studies. These are Esposito 1990, Esposito 1992 and Povendano 1995. None of these three papers includes a group which uses antiseptics. They all use topical antibiotics.

It would be helpful for developing countries and doctors in the developed world if the authors could make a "recommendation" about the different forms of topical antiseptics. This could be very useful for cash strapped developing countries and for difficult cases in the developing world.

Contributors

Bruce Arroll MBChB, PhD 
 Department of General Practice 
 University of Auckland 
 Private Bag 92019 
 Auckland 
 New Zealand

E‐mail: b.arroll@auckland.ac.nz

What's new

Date Event Description
22 October 2008 Amended Converted to new review format.

History

Protocol first published: Issue 4, 1998
 Review first published: Issue 4, 1998

Date Event Description
12 June 1998 New citation required and conclusions have changed Substantive amendment

Sources of support

Internal sources

  • De La Salle University (DLSU) College of Medicine, Philippines.

External sources

  • British Council Link grant to DLSU and Liverpool School of Tropical Medicine, UK.

  • Overseas Development Administration, UK.

Withdrawn from publication for reasons stated in the review


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