Table 1.
Salient investigations for suspected SAPH.
| Investigations | Salient Parameters |
|---|---|
| Electrocardiogram | Features of PH |
| Lung function test | Disproportionate reduction in DLCO; Kco |
| Six-minute walk test | Six-minute walk distance and desaturation |
| Arterial blood gas sample | Alveolar-arterial gradient |
| Blood test sample | BNP or NT-proBNP |
| Chest CT | MPA/AA diameter ratio, pulmonary fibrosis |
| CMR | RV dysfunction and PH features |
| Echocardiography | Probability of pulmonary hypertension |
AA: ascending aorta; BNP: B-type natriuretic peptide; CMR: cardiovascular magnetic resonance; CT: computed tomography; DLCO: diffusing capacity for carbon monoxide; Kco: carbon monoxide transfer coefficient; MPA: main pulmonary artery; NT-proBNP: N-terminal Pro-BNP; PH: pulmonary hypertension; RV: right ventricular.