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. 2024 Jan 5;12(1):112. doi: 10.3390/microorganisms12010112

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Structural alignment of the minimized G6PD::6PGL models. Structural alignment of the human G6PD enzyme (PDB entry 2BH9; blue cartoon) and the minimized model of (A) GlG6PD::6PGL from G. lamblia. G6PD domain is shown in blue cartoon; 6PGL domain in orange cartoon (B) Alignment of HuG6PD vs. GlG6PD::6PGL. (C) TvG6PD::6PGL from T. vaginalis. G6PD domain is shown in yellow cartoon; 6PGL domain in green cartoon (D) Alignment of HuG6PD vs. TvG6PD::6PGL. (E) PfGluPhos from P. falciparum. G6PD domain is shown in pink cartoon; 6PGL domain in cyan cartoon (F) Alignment of HuG6PD vs. PfGluPhos.