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. 2024 Jan 5;16(1):80. doi: 10.3390/pharmaceutics16010080

Scheme 1.

Scheme 1

Synthesis of chitosan-based QPSs reported and prepared by Wang et al. [148]. Preparation of the quaternary phosphonium carboxylic acids (1); esterification of chitosan with the quaternary phosphonium carboxylic acids (2). EDC = 1-ethyl-3-(3-dimethylaminopropyl) carbodiimide; NHS = N-Hydroxy-succinimide.