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. 2024 Jan 14;16(1):120. doi: 10.3390/v16010120

Figure 1.

Figure 1

mRNA iLNP vaccine-induced immune response. (A) Innate immune response induced by iLNP and mRNA, separately. (B) Adaptive immune response induced by mRNA iLNP. PRR, pattern recognition receptor; Nlrp3, NOD-, LRR- and pyrin domain-containing protein 3; ASC, apoptosis-associated speck-like protein containing a caspase recruitment domain; TLR, toll-like receptor; RIG-1, retinoic acid-inducible gene 1; MDA5, melanoma differentiation association protein 5; NF-κB, nuclear factor- κB; MyD88, myeloid differentiation marker 88; TFH, T follicular helper cell; IFN, interferon; IL, interleukin. The figure was created with BioRender.com and was last accessed on 13 January 2024.