Table 4.

Independent predictors of 30-day all-cause mortality based on hierarchical multiple logistic regression

Variables	Model 1			Model 2			Model 3			Model 4
	Odds ratio	95% CI	p	Odds ratio	95% CI	p	Odds ratio	95% CI	p	Odds ratio	95% CI	p
Age (years)	1.06	1.04–1.08	< 0.001	1.06	1.04–1.08	< 0.001	1.06	1.04–1.09	< 0.001	1.06	1.04–1.09	< 0.001
Hypertension	1.04	0.53–2.02	0.912	1.18	0.6–2.32	0.629	1.04	0.51–2.1	0.922	0.96	0.47–1.97	0.915
Chronic kidney disease	2.73	1.57–4.77	< 0.001	2.96	1.67–5.25	< 0.001	2.96	1.62–5.4	< 0.001	2.97	1.63–5.44	< 0.001
Currently active malignancy	2.28	1.24–4.2	0.008	2.62	1.39–4.92	0.003	2.59	1.33–5.03	0.005	2.64	1.35–5.13	0.004
Past history of malignancy	0.76	0.27–2.12	0.595	0.72	0.25–2.08	0.545	0.62	0.2–1.88	0.393	0.63	0.21–1.92	0.416
Vaccination status						0.057			0.027			0.024
Linear				0.51	0.29–0.89	0.017	0.45	0.25–0.81	0.007	0.44	0.24–0.79	0.006
Deviation				0.89	0.58–1.37	0.589	0.83	0.52–1.3	0.412	0.84	0.53–1.32	0.441
Lymphocytes (%)							0.97	0.94–1	0.036	0.97	0.94–1	0.042
C-reactive protein (mg/l)							1.01	1–1.01	< 0.001	1.01	1–1.01	< 0.001
Atrial fibrillation										1.86	0.93–3.71	0.078

95% CI, 95% confidence interval

Model 1, independent predictors of vaccination (age, hypertension, chronic kidney disease, currently active malignancy, past history of malignancy; method: enter)

Model 2, model 1 + vaccination status (no or partial — 0, full primary — 1, booster — 2; method: enter, contrast: polynomial)

Model 3, model 2 + laboratory measures (white blood cell count, neutrophils, lymphocytes, procalcitonin, C-reactive protein, serum creatinine, serum albumin; method: backward stepwise)

Model 4, model 3 + medical history (diabetes mellitus, hyperlipidaemia, myocardial infarction/heart failure, stroke, atrial fibrillation, dementia; method: backward stepwise)