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Journal of Neurology, Neurosurgery, and Psychiatry logoLink to Journal of Neurology, Neurosurgery, and Psychiatry
. 1982 Feb;45(2):97–101. doi: 10.1136/jnnp.45.2.97

Clinical factors associated with dementia in ischaemic stroke.

G Ladurner, L D Iliff, H Lechner
PMCID: PMC1083034  PMID: 7069439

Abstract

71 patients with an ischaemic stroke were studied. The patients were separated into two groups on the basis of the results of clinical investigation, computed tomography and psychological testing (WAIS). 40 patients showed an early dementia and 31 were without mental impairment. The mean age was 57 years in the demented group and 54 years in the non-demented group. The mean duration of the history of cerebrovascular disease was also not statistically different in both groups. The frequency of strokes was identical since 50% of the patients in both groups had more than one stroke. The history of neurological symptoms together with the neurological deficits seen on admission were distributed evenly. The dominant hemisphere was more often diseased in the demented group. Bilateral symptoms were also more common in the demented stroke patients. The WAIS showed a similar IQ in both groups but the deterioration index was significantly altered in the demented group. Hypertension was the only risk factor which differed between both groups. Cardiac disease, diabetes, viscosity and fibrinogen did not differ in both groups. The CT showed more normal scans in the non-demented group, the distribution of atrophy on its own and infarction in the left or right hemisphere were both inconclusive, whilst patients with bilateral infarcts were more common in the dementia group. Also, generalised atrophy in combination with an infarct was found more often in the demented patients.

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Selected References

These references are in PubMed. This may not be the complete list of references from this article.

  1. Alcalá H., Gado M., Torack R. M. The effect of size, histologic elements, and water content on the visualization of cerebral infarcts. Arch Neurol. 1978 Jan;35(1):1–7. doi: 10.1001/archneur.1978.00500250005001. [DOI] [PubMed] [Google Scholar]
  2. Broe G. A., Akhtar A. J., Andrews G. R., Caird F. I., Gilmore A. J., McLennan W. J. Neurological disorders in the elderly at home. J Neurol Neurosurg Psychiatry. 1976 Apr;39(4):362–366. doi: 10.1136/jnnp.39.4.362. [DOI] [PMC free article] [PubMed] [Google Scholar]
  3. Hachinski V. C., Iliff L. D., Zilhka E., Du Boulay G. H., McAllister V. L., Marshall J., Russell R. W., Symon L. Cerebral blood flow in dementia. Arch Neurol. 1975 Sep;32(9):632–637. doi: 10.1001/archneur.1975.00490510088009. [DOI] [PubMed] [Google Scholar]
  4. Ingvar D. H., Gustafson L. Regional cerebral blood flow in organic dementia with early onset. Acta Neurol Scand. 1970;46(Suppl):42+–42+. doi: 10.1111/j.1600-0404.1970.tb02156.x. [DOI] [PubMed] [Google Scholar]
  5. Jellinger K. Neuropathological aspects of dementias resulting from abnormal blood and cerebrospinal fluid dynamics. Acta Neurol Belg. 1976 Mar-Apr;76(2):83–102. [PubMed] [Google Scholar]
  6. Kay D. W., Bergmann K., Foster E. M., McKechnie A. A., Roth M. Mental illness and hospital usage in the elderly: a random sample followed up. Compr Psychiatry. 1970 Jan;11(1):26–35. doi: 10.1016/0010-440x(70)90201-4. [DOI] [PubMed] [Google Scholar]
  7. Kinkel W. R., Jacobs L. Computerized axial transverse tomography in cerebrovascular disease. Neurology. 1976 Oct;26(10):924–930. doi: 10.1212/wnl.26.10.924. [DOI] [PubMed] [Google Scholar]
  8. LASSEN N. A., FEINBERG I., LANE M. H. Bilateral studies of cerebral oxygen uptake in young and aged normal subjects and in patients with organic dementia. J Clin Invest. 1960 Mar;39:491–500. doi: 10.1172/JCI104063. [DOI] [PMC free article] [PubMed] [Google Scholar]
  9. Ladurner G., Bertha G., Pieringer W., Lytwin H., Lechner H. Klinische Unterscheidungskriterien bei vaskulärer (Multiinfarkt) und primär degenerativer Demenz (Alzheimer). Nervenarzt. 1981 Jul;52(7):401–404. [PubMed] [Google Scholar]
  10. Ladurner G., Sager W. D., Iliff L. D., Lechner H. A correlation of clinical findings and CT in ischaemic cerebrovascular disease. Eur Neurol. 1979;18(5):281–288. doi: 10.1159/000115091. [DOI] [PubMed] [Google Scholar]
  11. Ladurner G., Sager W. D. Morphologische Bedigungskonstellation der vaskulären (Multiinfarkt) Demenz. Fortschr Neurol Psychiatr. 1981 Feb;49(2):53–55. doi: 10.1055/s-2007-1002307. [DOI] [PubMed] [Google Scholar]
  12. MUNCK O., LASSEN N. A. Bilaterial cerebral blood flow and oxygen comsumption in man by use of krypton 85. Circ Res. 1957 Mar;5(2):163–168. doi: 10.1161/01.res.5.2.163. [DOI] [PubMed] [Google Scholar]
  13. Sager W. D., Ladurner G. Klassifikation und Verlauf des Hirninfarktes im Computertomogramm. Rofo. 1979 Nov;131(5):470–475. doi: 10.1055/s-0029-1231474. [DOI] [PubMed] [Google Scholar]
  14. Zeumer H., Schonsky B., Sturm K. W. Predominant white matter involvement in subcortical arteriosclerotic encephalopathy (Binswanger disease). J Comput Assist Tomogr. 1980 Feb;4(1):14–19. doi: 10.1097/00004728-198002000-00003. [DOI] [PubMed] [Google Scholar]

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