Abstract
Ten patients with myotonic dystrophy were allocated at random to treatment with disopyramide and procainamide in a cross-over trial. Disopyramide was found to be at least as effective as procainamide in the relief of myotonia; and two patients who could not tolerate procainamide both tolerated disopyramide.
Full text
PDF


Selected References
These references are in PubMed. This may not be the complete list of references from this article.
- GESCHWIND N., SIMPSON J. A. Procaine amide in the treatment of myotonia. Brain. 1955;78(1):81–91. doi: 10.1093/brain/78.1.81. [DOI] [PubMed] [Google Scholar]
- Kus T., Sasyniuk B. I. Disopyramide phosphate: is it just another quinidine. Can J Physiol Pharmacol. 1978 Apr;56(2):326–331. doi: 10.1139/y78-049. [DOI] [PubMed] [Google Scholar]
- LEYBURN P., WALTON J. N. The treatment of myotonia: a controlled clinical trial. Brain. 1959 Mar;82(1):81–91. doi: 10.1093/brain/82.1.81. [DOI] [PubMed] [Google Scholar]
- McComas A. J., Campbell M. J., Sica R. E. Electrophysiological study of dystrophia myotonica. J Neurol Neurosurg Psychiatry. 1971 Apr;34(2):132–139. [PMC free article] [PubMed] [Google Scholar]
- McComas A. J., Sica R. E., Toyonaga K. Incidence, severity, and time-course of motoneurone dysfunction in myotonic dystrophy: their significance for an understanding of anticipation. J Neurol Neurosurg Psychiatry. 1978 Oct;41(10):882–893. doi: 10.1136/jnnp.41.10.882. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Munsat T. L. Therapy of myotonia. A double-blind evaluation of diphenylhydantoin, procainamide, and placebo. Neurology. 1967 Apr;17(4):359–367. doi: 10.1212/wnl.17.4.359. [DOI] [PubMed] [Google Scholar]