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. Author manuscript; available in PMC: 2024 Dec 1.
Published in final edited form as: Anesthesiology. 2023 Dec 1;139(6):880–898. doi: 10.1097/ALN.0000000000004734

Table 1.

Diagnostic criteria for RIFLE, AKIN and KDIGO. RIFLE, Risk, Injury, Failure, Loss, and End-stage renal failure. AKIN, Acute Kidney Injury Network. KDIGO, Kidney Disease: Improving Global Outcomes. SCr, Serum creatinine. GFR, Glomerular Filtration Rate. RRT, Renal Replacement Therapy.

RIFLE AKIN KDIGO
Class Creatinine Criteria Urine Output Criteria Stage Creatinine Criteria Urine Output Criteria Stage Creatinine Criteria Urine Output Criteria
Risk SCr ≥ 1.5 times baseline OR GFR decline ≥ 25% <0.5 mL/kg/h for ≥6 h Stage 1 SCr ≥ 1.5 times baseline or increase by 0.3 mg/dL within 48 hours <0.5 mL/kg/h for ≥6 h Stage 1 SCr increase by 0.3 mg/dL within 48 hours OR SCr ≥ 1.5–1.9 times baseline within 7 days <0.5 mL/kg/h for ≥6 h
Injury SCr ≥ 2 times baseline OR GFR decline ≥ 50% <0.5 mL/kg/h for ≥12 h Stage 2 SCr ≥ 2 times baseline <0.5 mL/kg/h for ≥12 h Stage 2 SCr ≥ 2.0–2.9 times baseline within 7 days <0.5 mL/kg/h for ≥12 h
Failure SCr ≥ 3 times baseline or increase by 0.5 mg/dL to ≥ 4 mg/dL OR GFR decline ≥ 75% OR RRT Initiation <0.3 mL/kg/h for 24 h OR Anuria for 12 h Stage 3 SCr ≥ 3 times baseline or increase by 0.5 mg/dL to ≥ 4 mg/dL OR RRT Initiation <0.3 mL/kg/h for 24 h OR Anuria for 12 h Stage 3 SCr ≥ 3 times baseline or increase by 0.5 mg/dL to ≥ 4 mg/dL OR RRT Initiation <0.3 mL/kg/h for 24 h OR Anuria for 12 h
Loss Loss of renal function for ≥ 4 weeks
End-Stage Loss of renal function for ≥ 3 months