Abstract
Dementia of Lewy body disease is the second most common degenerative cause of dementia after Alzheimer's disease, among all the dementias. The core features are a progressive dementia, fluctuations in cognitive functions, visual hallucinations, and spontaneous parkinsonism. Rapid eye movement sleep behavior disorder, severe neuroleptic sensitivity, and low dopamine transporter uptake in basal ganglia are other suggestive features. Behavioral abnormalities are commonly present in the form of aggressive behavior, irritability, and disinhibited behaviors. These are mostly seen in the advanced stages of dementia. However, inappropriate sexual behavior is uncommonly seen in such cases. Three types of inappropriate sexual behaviors commonly found in cases of dementia are sex talks, sexual acts, and implied sexual acts. Such inappropriate sexual behaviors have not been described adequately in dementia of Lewy body disease. We report inappropriate sexual behaviors in a case of dementia of Lewy body disease, which improved rapidly after treatment with quetiapine.
Keywords: Lewy body disease, Inappropriate sexual behavior, Dementia
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Contributor Information
Ravi Prakash, Central Institute of Psychiatry, Ranchi, India, drravi2121@gmail.com .
Amit Pathak, Central Institute of Psychiatry, Ranchi, India.
Sanjay Munda, Central Institute of Psychiatry, Ranchi, India.
Dhruv Bagati, Central Institute of Psychiatry, Ranchi, India.
References
- Rahkonen T., Eloniemi-Sulkava U., Rissanen S., Vatanen A., Viramo P., Sulkava R. Dementia with Lewy bodies according to the consensus criteria in a general population aged 75 years or older. J Neurol Neurosurg Psychiatry . 2003;74: 720-724. [DOI] [PMC free article] [PubMed] [Google Scholar]
- Perry RH, Irving D., Blessed G., Perry EK, Fairbairn AF Clinically and neuropathologically distinct form of dementia in the elderly . Lancet. 1989;1:166. [DOI] [PubMed] [Google Scholar]
- McKeith IG, Galasko D., Kosaka K., et al. Consensus guidelines for the clinical and pathologic diagnosis of dementia with Lewy bodies (DLB): report of the consortium on DLB international workshop. Neurology. 1996;47: 1113-1124. [DOI] [PubMed] [Google Scholar]
- McKeith IG, Dickson DW, Lowe J., et al. Diagnosis and management of dementia with Lewy bodies: third report of the DLB consortium. Neurology. 2005. ;65: 1863-1872. [DOI] [PubMed] [Google Scholar]
- McKeith IG, Perry EK, Perry RH Report of the second dementia with Lewy body international workshop: diagnosis and treatment: consortium on dementia with Lewy bodies. Neurology . 1999;53:902-905. [DOI] [PubMed] [Google Scholar]
- Szasz G. Sexual incidents in an extended care unit for aged men. J Am Geriatr Soc. 1983;31:407-411. [DOI] [PubMed] [Google Scholar]
- Black B., Muralee S., Tampi RR Inappropriate Sexual Behaviors in Dementia. Geriatr Psychiatry Neurol. 2005; 18:155-162. [DOI] [PubMed] [Google Scholar]
- Wszolek ZK, Tsuboi Y., Farrer M., Uitti RJ, Hutton ML Hereditary tauopathies and parkinsonism. Adv Neurol. 2003;91:153-163. [PubMed] [Google Scholar]
- McKeith I. Dementia with Lewy bodies and Parkinson's disease with dementia: where two worlds collide. Pract Neurol. 2007;7:374-382. [DOI] [PubMed] [Google Scholar]
- Papka M., Rubio A., Schiffer RB A review of Lewy body disease, an emerging concept of cortical dementia. J Neuropsychiatry Clin Neurosci. 1998;10:267-279.11. [DOI] [PubMed] [Google Scholar]
- Harding AJ, Broe GA, Halliday GM Visual hallucinations in Lewy body disease relate to Lewy bodies in the temporal lobe. Brain. 2002;125:391-403. [DOI] [PubMed] [Google Scholar]
- Engelborghs S., Maertens K., Mariën P., et al. Behavioural and neuropsychological correlates of frontal lobe features in dementia. Psychol Med . 2006;36: 1173-1182. [DOI] [PubMed] [Google Scholar]
- Onor ML, Saina M., Eugenio A. Efficacy and tolerability of quetiapine in the treatment of behavioral and psychological symptoms of dementia. Am J Alzheimers Dis Other Demen. 2006;21:448-453. [DOI] [PubMed] [Google Scholar]
- Hashmi FH, Krady AL, Qayum F., Grossberg GT Sexually disinhibited behavior in the cognitively impaired elderly. Clin Geriatr. 2000;8:631-637. [Google Scholar]
- Macknight C. , Rojas-Fernandez C. Quetiapine for sexually inappropriate behavior in dementia. J Am Geriatr Soc. 2000;48:707. [DOI] [PubMed] [Google Scholar]