Fig 1 is erroneously duplicated as Fig 5. Please see the correct Fig 5 here.
Fig 5. Targeting different stages of the protein synthesis process enhances readthrough mediated by non-aminoglycosides.
(A) The APC R1450X reporter cell line was treated for 24 h with 10 μm Escin or 200 μm Ataluren and 50 μm 4EGI-1, 100 μm A-484954 or 5 μm SRI-41315. (B) The APC R1450X reporter cell line (upper blot) and Colo320 cell line (lower blot) were treated for 24 h with 300 μg/ml Erythromycin and 50 μm 4EGI-1, 100 μm A-484954 or 5 μm SRI-41315. APC, adenomatous polyposis coli.
Reference
- 1.Wittenstein A, Caspi M, Rippin I, Elroy-Stein O, Eldar-Finkelman H, Thoms S, et al. (2023) Nonsense mutation suppression is enhanced by targeting different stages of the protein synthesis process. PLoS Biol 21(11): e3002355. doi: 10.1371/journal.pbio.3002355 [DOI] [PMC free article] [PubMed] [Google Scholar]

