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. 2005 May 2;115(5):1388. doi: 10.1172/JCI200523187C1

Complementary roles of IRS-1 and IRS-2 in the hepatic regulation of metabolism

Cullen M Taniguchi, Kohjiro Ueki, C Ronald Kahn
PMCID: PMC1087166

Original citation: J. Clin. Invest. 115:718–727 (2005). doi:10.1172/JCI200523187

Citation for this corrigendum: J. Clin. Invest. 115:1388 (2005). doi:10.1172/JCI200523187C1

Due to an error in manuscript preparation, an incorrect shRNA sequence for IRS2 was published. The correct hairpin sequence is a 19-nt stretch beginning from nt 703 of the published IRS2 cDNA sequence (XM_357863). The oligonucleotides cloned into the U6 construct for the IRS2U6 adenovirus are as follows: tcgagGTGACGCTGCAGCTTATGAttcaagagaTCATAAGCTGCAGCGTCACttttt (forward) and ctagAAAAAGTGACGCTGCAGCTTATGAtctcttgaaTCATAAGCTGCAGCGTCACc (reverse). In addition, the shRNA cassettes were cloned into the adenoviral cosmid pAxcwit, which lacks a promoter, and not the cosmid pAxCAwtit, as published.

The authors regret this error.


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