Figure 5. Concentrations up to 40μg/mL of ML are not toxic to human cells and can significantly decrease S. brasiliensis survival in A549 epithelial cells.

a) A459 epithelial cells were treated with different ML concentrations, with a decrease of cell viability only at 80μg/mL or higher concentrations. b) A459 cells were challenged with S. brasiliensis yeast at a proportion of 1:10 and 1:20 and then treated with 20 and 40μg/mL of ML. The fungicidal drug TRB was included as a control. **p-value<0.01 when compared to untreated cells. ****p-value<0.0001 when compared to untreated cells. #p-value<0.0001 when compared to cells treated with TRB.