The journal retracts the article “Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment” [1] cited above.
Following publication, concerns were brought to the attention of the publisher regarding the overlap of images across a number of publications.
Adhering to our complaints procedure, an investigation was conducted by the Editorial Office and Editorial Board that confirmed the overlap of Figure 4 published in [1] with Figure 8 of [2], Figure 7 of [3], Figure 7 [4], Figure 7 of [5], Figure 7 of [6], and Figure S2 of [7], listing different experimental conditions.
While the authors fully cooperated with the Editorial Office during the investigation, they were unable to satisfactorily explain the overlap of figures presenting different experimental conditions and meet the required quality standards of raw images to consider a correction as per the journal’s original image requirements policy (https://www.mdpi.com/journal/pharmaceutics/instruc-tions#oriimages). As a result, the Editorial Board and Editor-in-Chief were unable to confirm the reliability of the findings and subsequently decided to retract this paper as per MDPI’s retraction policy (https://www.mdpi.com/ethics#_bookmark30).
This retraction was approved by the Editor-in-Chief of the journal Pharmaceutics.
The authors did not agree to this retraction.
Footnotes
Disclaimer/Publisher’s Note: The statements, opinions and data contained in all publications are solely those of the individual author(s) and contributor(s) and not of MDPI and/or the editor(s). MDPI and/or the editor(s) disclaim responsibility for any injury to people or property resulting from any ideas, methods, instructions or products referred to in the content.
References
- 1.Aldawsari H.M., Ahmed O.A.A., Alhakamy N.A., Neamatallah T., Fahmy U.A., Badr-Eldin S.M. RETRACTED: Lipidic Nano-Sized Emulsomes Potentiates the Cytotoxic and Apoptotic Effects of Raloxifene Hydrochloride in MCF-7 Human Breast Cancer Cells: Factorial Analysis and In Vitro Anti-Tumor Activity Assessment. Pharmaceutics. 2021;13:783. doi: 10.3390/pharmaceutics13060783. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
- 2.Awan Z.A., A. Fahmy U., Badr-Eldin S.M., Ibrahim T.S., Asfour H.Z., Al-Rabia M.W., Alfarsi A., Alhakamy N.A., Abdulaal W.H., Al Sadoun H., et al. The Enhanced Cytotoxic and Pro-Apoptotic Effects of Optimized Simvastatin-Loaded Emulsomes on MCF-7 Breast Cancer Cells. Pharmaceutics. 2020;12:597. doi: 10.3390/pharmaceutics12070597. [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]
- 3.Alhakamy N.A., Badr-Eldin S.M., Ahmed O.A.A., Asfour H.Z., Aldawsari H.M., Algandaby M.M., Eid B.G., Abdel-Naim A.B., Awan Z.A., Alghaith A.F., et al. Piceatannol-Loaded Emulsomes Exhibit Enhanced Cytostatic and Apoptotic Activities in Colon Cancer Cells. Antioxidants. 2020;9:419. doi: 10.3390/antiox9050419. [DOI] [PMC free article] [PubMed] [Google Scholar]
- 4.Alhakamy N.A., Badr-Eldin S.M., Aldawsari H.M., Alfarsi A., Neamatallah T., Okbazghi S.Z., Fahmy U.A., Ahmad O.A.A., Eid B.G., Mahdi W.A., et al. Retraction Note: Fluvastatin-Loaded Emulsomes Exhibit Improved Cytotoxic and Apoptosis in Prostate Cancer Cells. AAPS PharmSciTech. 2023;24:128. doi: 10.1208/s12249-023-02591-y. [DOI] [PubMed] [Google Scholar]
- 5.Badr-Eldin S.M., Aldawsari H.M., Ahmed O.A.A., Alhakamy N.A., Neamatallah T., Okbazghi S.Z., Fahmy U.A. Optimized semisolid self-nanoemulsifying system based on glyceryl behenate: A potential nanoplatform for enhancing antitumor activity of raloxifene hydrochloride in MCF-7 human breast cancer cells. Int. J. Pharm. 2021;600:120493. doi: 10.1016/j.ijpharm.2021.120493. [DOI] [PubMed] [Google Scholar]
- 6.Alhakamy N.A., Badr-Eldin S.M., A. Fahmy U., Alruwaili N.K., Awan Z.A., Caruso G., Alfaleh M.A., Alaofi A.L., Arif F.O., Ahmed O.A.A., et al. Thymoquinone-Loaded Soy-Phospholipid-Based Phytosomes Exhibit Anticancer Potential against Human Lung Cancer Cells. Pharmaceutics. 2020;12:761. doi: 10.3390/pharmaceutics12080761. [DOI] [PubMed] [Google Scholar]
- 7.Alhakamy N.A., A. Fahmy U., Badr-Eldin S.M., Ahmed O.A.A., Asfour H.Z., Aldawsari H.M., Algandaby M.M., Eid B.G., Abdel-Naim A.B., Awan Z.A., et al. Optimized Icariin Phytosomes Exhibit Enhanced Cytotoxicity and Apoptosis-Inducing Activities in Ovarian Cancer Cells. Pharmaceutics. 2020;12:346. doi: 10.3390/pharmaceutics12040346. [DOI] [PubMed] [Google Scholar]