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. 2024 Feb 24;17:161–162. doi: 10.2147/OTT.S465407

SIRT6 Overexpression Induces Apoptosis of Nasopharyngeal Carcinoma by Inhibiting NF-κB Signaling [Retraction]

PMCID: PMC10901746  PMID: 38426082

Ouyang L, Yi L, Li J, et al. Onco Targets Ther. 2018;11:7613–7624.

We, the Editors and Publisher of OncoTargets and Therapy, have retracted the following article.

Following publication of the article, concerns were raised about the duplication of images from Figures 1, 2, 3, 4 and 5 with images from other unrelated articles. Specifically,

  • Images for Figure 1D have been duplicated with images for Figure 3h from Bai Z, Zhao X, Li C, et al. RETRACTED ARTICLE: EV71 virus reduces Nrf2 activation to promote production of reactive oxygen species in infected cells. Gut Pathog. 2020;12:22. https://doi.org/10.1186/s13099-020-00361-w.

  • Images for Figures 2A, 3C, and 5A have been duplicated with images for Figures 3C and 3D from Zhou J, Zhang Y, Han Z, et al. RETRACTED ARTICLE: miR-506 contributes to malignancy of cutaneous squamous cell carcinoma via targeting of P65 and LAMC1. Cell Cycle. 2019;18(3):333-345. https://doi.org/10.1080/15384101.2019.1568747.

  • Images for Figures 2A, 4C, 4D and 4F have been duplicated with images for Figures 6a and 6b from Zhong R, Li S, Fang K, Yang L, Wang L. microRNA-1225 inhibit apoptosis of pancreatic cancer cells via targeting JAK1. Cell Cycle. 2019;18(9):990-1000. https://doi.org/10.1080/15384101.2019.1608127.

  • Images for Figure 3A have been duplicated with images for Figure 3C from Wang Y, Zhang X, Song Z, Gu F. An anti-CAPN5 intracellular antibody acts as an inhibitor of CAPN5-mediated neuronal degeneration. Oncotarget. 2017;8:100312-100325. https://doi.org/10.18632/oncotarget.22221.

  • Images for Figure 4C have been duplicated with images for Figures 6A and 6B from Song Z, Wang H, Zong F, Zhu C, Tao Y. MicroRNA-506 regulates apoptosis in retinoblastoma cells by targeting sirtuin 1. Cancer Manag Res. 2019;11:8419-8429. https://doi.org/10.2147/CMAR.S211122 and Figure 8A from Huang L, Jian Z, Gao Y, et al. RPN2 promotes metastasis of hepatocellular carcinoma cell and inhibits autophagy via STAT3 and NF-κB pathways. Aging (Albany NY). 2019;11:6674-6690. https://doi.org/10.18632/aging.102167.

The authors responded to our queries but were unable to provide an explanation for the duplicated images or provide data for the study. As verifying the validity of published work is core to the integrity of the scholarly record, we are therefore retracting the article and the authors agree with this decision.

We have been informed in our decision-making by our editorial policies and COPE guidelines.

The retracted article will remain online to maintain the scholarly record, but it will be digitally watermarked on each page as “Retracted”.


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