On 20 September 2017, Science Advances published the Research Article “Structural analysis of BRCA1 reveals modification hotspot” by Liang et al. (1). In May 2023, concerns were raised related to EMD-8834 Wild type BRCA1-BARD1 and EMD-8833 Mutated BRCA1-BARD1 and were promptly reviewed by the journal. The concerns were cleared after internal review. The editors have now been made aware of additional concerns related to the paper on PubPeer. We are alerting readers to these concerns while the journal reviews these issues.
Reference
- 1.Liang Y., Dearnaley W. J., Varano A. C., Winton C. E., Gilmore B. L., Alden N. A., Sheng Z., Kelly D. F., Structural analysis of BRCA1 reveals modification hotspot. Sci. Adv. 3, e1701386 (2017). [DOI] [PMC free article] [PubMed] [Google Scholar] [Retracted]