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. 2024 Mar 14;15(3):214. doi: 10.1038/s41419-024-06517-9

Correction: Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling

Lingting Jin 1,2,3,#, Jingjing Zhang 2,#, Xin Hua 2,#, Xingxing Xu 2, Jia Li 1, Jiaojiao Wang 2, Mianxian Wang 2, Huitao Liu 2, Haoyu Qiu 2, Man Chen 2, Xu Zhang 1,, Ying Wang 4,, Zhihui Huang 1,2,3,
PMCID: PMC10940651  PMID: 38485949

Correction to: Cell Death and Disease 10.1038/s41419-022-05202-z, published online 02 September 2022

In this article, in Fig. 2C, the Nissl staining of SARMlf/f as a control and Fig. 5E were identical.graphic file with name 41419_2024_6517_Figa_HTML.jpg

Fig. 2 EAE was relieved with later onset, less inflammatory infiltration, and fewer neuronal death in SARM1GFAP-CKO mice. A The weight of SARM1f/f mice and SARM1GFAP-CKO mice, and SARM1f/f EAE mice and SARM1GFAP-CKO EAE mice ranged from 0 to 21 dpi (n = 5, two-way ANOVA with Bonferroni’s post-tests). B The EAE score of SARM1f/f and SARM1GFAP-CKO mice ranged from 0 to 21 dpi (n = 5, two-way ANOVA with Bonferroni’s post-tests). C Typical images of Nissl staining in the lumbar spinal cords of SARM1f/f mice and SARM1GFAP-CKO mice, and SARM1f/f EAE mice and SARM1GFAP-CKO EAE mice. D Quantitative analysis of density of Nissl bodies as shown in (C) (n = 5). E Typical images of NeuN+ immunostaining in the lumbar spinal cords of SARM1f/f and SARM1GFAP-CKO mice, and SARM1f/f EAE and SARM1GFAP-CKO EAE mice. F Quantitative analysis of the density of NeuN+ cells as shown in (E) (n = 5). G Typical images of HE staining in the lumbar spinal cords in of SARM1f/f mice and SARM1GFAP-CKO mice, and SARM1f/f EAE mice and SARM1GFAP-CKO EAE mice. H Quantitative analysis of the density of infiltrating cells as shown in (G) (n = 5). I The typical images of CD45+ immunostaining in the lumbar spinal cords of SARM1f/f mice and SARM1GFAP-CKO mice, and SARM1f/f EAE mice and SARM1GFAP-CKO EAE mice. J Quantitative analysis of the density of CD45+ cells as shown in (I) (n = 5). Scale bar, 50 μm. The data were mean ± SEM. Student’s t-test unless otherwise indicated, n.s., not significant (p > 0.05), **p < 0.01, ***p < 0.001.

The figure should be read:graphic file with name 41419_2024_6517_Figb_HTML.jpg

The original article has been corrected.

Contributor Information

Xu Zhang, Email: drzhangxu@live.cn.

Ying Wang, Email: nancywangying@163.com.

Zhihui Huang, Email: huang0069@hznu.edu.cn.


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