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. 2024 Mar 14;15(3):214. doi: 10.1038/s41419-024-06517-9

Correction: Astrocytic SARM1 promotes neuroinflammation and axonal demyelination in experimental autoimmune encephalomyelitis through inhibiting GDNF signaling

Lingting Jin 1,2,3,#, Jingjing Zhang 2,#, Xin Hua 2,#, Xingxing Xu 2, Jia Li 1, Jiaojiao Wang 2, Mianxian Wang 2, Huitao Liu 2, Haoyu Qiu 2, Man Chen 2, Xu Zhang 1,✉, Ying Wang 4,✉, Zhihui Huang 1,2,3,✉
PMCID: PMC10940651  PMID: 38485949

Correction to: Cell Death and Disease 10.1038/s41419-022-05202-z, published online 02 September 2022

In this article, in Fig. 2C, the Nissl staining of SARMlf/f as a control and Fig. 5E were identical.graphic file with name 41419_2024_6517_Figa_HTML.jpg

Fig. 2 EAE was relieved with later onset, less inflammatory infiltration, and fewer neuronal death in SARM1GFAP-CKO mice. A The weight of SARM1f/f mice and SARM1GFAP-CKO mice, and SARM1f/f EAE mice and SARM1GFAP-CKO EAE mice ranged from 0 to 21 dpi (n = 5, two-way ANOVA with Bonferroni’s post-tests). B The EAE score of SARM1f/f and SARM1GFAP-CKO mice ranged from 0 to 21 dpi (n = 5, two-way ANOVA with Bonferroni’s post-tests). C Typical images of Nissl staining in the lumbar spinal cords of SARM1f/f mice and SARM1GFAP-CKO mice, and SARM1f/f EAE mice and SARM1GFAP-CKO EAE mice. D Quantitative analysis of density of Nissl bodies as shown in (C) (n = 5). E Typical images of NeuN+ immunostaining in the lumbar spinal cords of SARM1f/f and SARM1GFAP-CKO mice, and SARM1f/f EAE and SARM1GFAP-CKO EAE mice. F Quantitative analysis of the density of NeuN+ cells as shown in (E) (n = 5). G Typical images of HE staining in the lumbar spinal cords in of SARM1f/f mice and SARM1GFAP-CKO mice, and SARM1f/f EAE mice and SARM1GFAP-CKO EAE mice. H Quantitative analysis of the density of infiltrating cells as shown in (G) (n = 5). I The typical images of CD45+ immunostaining in the lumbar spinal cords of SARM1f/f mice and SARM1GFAP-CKO mice, and SARM1f/f EAE mice and SARM1GFAP-CKO EAE mice. J Quantitative analysis of the density of CD45+ cells as shown in (I) (n = 5). Scale bar, 50 μm. The data were mean ± SEM. Student’s t-test unless otherwise indicated, n.s., not significant (p > 0.05), **p < 0.01, ***p < 0.001.

The figure should be read:graphic file with name 41419_2024_6517_Figb_HTML.jpg

The original article has been corrected.

Contributor Information

Xu Zhang, Email: drzhangxu@live.cn.

Ying Wang, Email: nancywangying@163.com.

Zhihui Huang, Email: huang0069@hznu.edu.cn.


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