. 2024 Mar 7;10(6):e27527. doi: 10.1016/j.heliyon.2024.e27527

Table 2.

Effect of diosmin on colonic histopathological scoring of inflammation, edema, and ulceration.

Animal groups	Histopathological scoring
Animal groups	Inflammation	Edema	Ulceration
Normal control	2.00 ± 0.68	0.00 ± 0.00	0.00 ± 0.00
DSS	51.67 ± 3.07*	43.33 ± 1.67*	52.50 ± 2.14*
DSS + SSZ	22.50 ± 1.12*^#	20.00 ± 2.24*^#	23.17 ± 1.01*^#
DSS + DIO 100	30.00 ± 3.65*^#	25.83 ± 2.71*^#	26.67 ± 1.67*^#
DSS + DIO 200	14.33 ± 1.48^#‡	10.00 ± 1.29^#†‡	7.67 ± 0.92^#†‡

Values are presented as means of 6 mice ± SEM. Statistical analysis was carried out using one-way ANOVA followed by Tukey's post hoc test. *^{, #, †, ‡} Significantly different from normal control, DSS-induced colitis, DSS + SSZ and DSS + DIO 100 mg/kg groups at p < 0.05, respectively. DSS: dextran sulfate sodium; SSZ: sulfasalazine; DIO: diosmin.