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. 2023 Apr 14;29(29):e202300008. doi: 10.1002/chem.202300008

Scheme 12.

Scheme 12

a) Gaoni's ring‐opening reactions of 1‐(arylsulfonyl) bicyclo[1.1.0]butanes (48). b) Umpolung reactivity facilitated by bridgehead deprotonation and subsequent alkylation. a Identity of major diastereomer unknown.