TABLE 1.
Characteristics of participants in GLUCOLD, NORM and Stop‐smoking cohorts
| GLUCOLD cohort | NORM cohort | Stop‐smoking cohort | ||||||
|---|---|---|---|---|---|---|---|---|
| Before smoke cessation | After 12 months of smoke cessation | |||||||
| COPD smokers (n = 38) | COPD ex‐smokers (n = 18) | Never‐smokers (n = 40) | Smoker (n = 37) | Healthy subjects (n = 5) | COPD‐subjects (n = 11) | Healthy subjects (n = 5) | COPD‐subjects (n = 11) | |
| Age (years) | 59.3 ± 7.6 | 63.3 ± 7.4 | 38.51 ± 18.86 | 41.55 ± 15.18 | 49.2 ± 5 | 56.2 ± 6.3 | 49.2 ± 5 | 56.2 ± 6.3 |
| Sex, (M/F, n) | 33/5 | 17/1 | 20/20 | 22/15 | 3/2 | 6/5 | 3/2 | 6/5 |
| BMI (kg/m2) | 25.0 (22.8–27.8) | 26.9 (22.1–28.0) | 23.4 ± 3.95 | 24 ± 3.47 | NA | NA | NA | NA |
| Smoking (pack‐years) | 41.8 (34.2–55.6) | 39.5. (31.3–52.5) | 0 | 18.75 ± 15.95 | 23.68 ± 5.99 | 36.23 ± 14.66 | 23.68 ± 5.99 | 36.23 ± 14.66 |
| Post‐BD FEV1 (% predicted) | 63.1 (56.4–69.4 | 65.0 (56.8–70.1) | 104.82 ± 10.67 | 102.8 ± 9.89 | 107.6 ± 4.93 | 70.55 ± 18.15 | 108.66 ± 10.96 | 73.56 ± 16.86 |
| Post‐BD FEV1/FVC | 47.8 (39.9–54.7) | 46.8 (40.2–51.1) | 83.8 ± 6.75 | 81.1 ± 5.85 | 81.29 ± 5.57 | 46.46 ± 32.09 | 82.41 + 3.70 | 55.37 + 23.53 |
Note: Data are presented as mean ± SD or median (interquartile range: 25th–75th percentile).
Abbreviations: FEV1, forced expiratory volume in 1 second; FEV1/VC, forced expiratory volume in 1 second (FEV1) to vital capacity (VC) ratio; FVC, forced vital capacity.