Figure 3.
Late development of ROs (day 150–210) reveals maturation of photoreceptors, the appearance of BCs and MCs
(A and B) UMAP plots of scRNA-seq of ROs at day 150 (A) and day 210 of differentiation (B).
(C‒F) Localization of individual (C and D) and pooled (E and F) clusters in ROs at day 150 (C and E), day 210 (D and F) of differentiation based on ST analyses. Cluster annotations and highly expressed markers are shown in Table S1 for scRNA-seq data and in Table S2 for ST data. For scRNA-seq 96 ROs were used for all days. 15 ROs were used at day 150 and 210 for ST. The scRNA-seq and ST were performed once at each time point.