Table 5.

The interactions between ligands with the best scores and amino acid residues of biotargets.

LOX-5 (6NCF)	Luteolin- 3,7-diglucoside	a: Thr104, His130, Leu163, Glu134, Pro164; b: Thr137, Val107(3); c: Arg101(Pi-Cation).
	Rutin	a: Arg68, Arg101, Glu134, His130, Thr137; b: Lys133, Val107(3).
	3,5-Dicaffeoylquinic acid	a: Arg68, Arg101, Val110, His130, Asp166, Glu108; b: His130, Leu66, Val107.
COX-1	Luteolin	a: Ser530(2), TYR385; b: Ala527(4), Gly526(2), Val349(2), Leu531.
	Isorhamnetin	a: Ser530(2), Met522, Ala527; b: Gly526(2), Ala527(4), Val349(2), Leu531.
	Chlorogenic acid	a: Tyr385, Ser530, Tyr385, Met522; b: Val349, Leu359, Ala527, Leu531.
COX-2	Isorhamnetin	a: Tyr341, Ser516, Ser339, Tyr371; Leu338(2); b: Val509, Val335.
	Luteolin	a: Tyr341, Ser516, Ile503, Phe504, Tyr371; b: Leu338, Val509(2), Leu338, Val335.
	4,5-Dicaffeoylquinic acid	a: Arg106, Tyr371, Gly512 b: Val509(3), Tyr341, Val102, Leu345, Ala502.
NMDA	4,5-Dicaffeoylquinic acid	a: Asn616(2), Asn614, Leu611, Asn616; b: Val644, Val639, Leu642, Met641, Ala645.
	Luteolin	a: Phe613, Leu611(2), Asn615(2); b: Val644(2), Val639, Leu642.