[Preprint]. 2024 Mar 16:2024.03.13.24304263. [Version 1] doi: 10.1101/2024.03.13.24304263

Table 2: Model fit parameters from each cohort for a selection of the methods.

See Supplementary Table 3 for further information on the model parameters from the other methods.

Model details	Diagnostic	Cohort
Fixed effects / random effects		ALSPAC		CHOP - European American		CHOP - African American		NFBC1966		NFBC1986		OBE
Fixed effects / random effects		Male	Female	Male	Female	Male	Female	Male	Female	Male	Female	Male	Female
Cubic slope / Cubic slope	R² conditional	0.83	Warning: Singular precision matrix in level -1	0.96	0.96	0.88	0.92	0.80	0.81	0.84	0.84	0.84	0.86
	R² marginal	0.31		0.32	0.35	0.48	0.58	0.30	0.31	0.30	0.31	0.68	0.70
	ICC	0.75		0.93	0.94	0.76	0.80	0.72	0.73	0.77	0.77	0.52	0.52
	RMSE	0.06		0.04	0.04	0.07	0.07	0.05	0.06	0.05	0.05	0.10	0.09
	Sigma	0.06		0.05	0.05	0.07	0.07	0.06	0.06	0.05	0.05	0.10	0.10
Linear splines / Linear splines	R² conditional	0.84	0.86	0.95	Warning: Singular precision matrix in level -1	0.94	0.96	Warning: Singular precision matrix in level -1	0.82	0.85	0.84	0.85	0.86
	R² marginal	0.33	0.40	0.33		0.35	0.44		0.32	0.31	0.32	0.68	0.70
	ICC	0.75	0.78	0.93		0.91	0.92		0.73	0.78	0.77	0.53	0.51
	RMSE	0.06	0.06	0.05		0.05	0.05		0.05	0.05	0.05	0.09	0.09
	Sigma	0.06	0.07	0.05		0.06	0.06		0.06	0.05	0.05	0.10	0.10
Cubic splines / Cubic splines	R² conditional	0.91	0.92	Warning: Singular precision matrix in level -1	Warning: Singular precision matrix in level -1	0.91	0.94	Warning: Singular precision matrix in level -1	0.89	0.90	0.90	0.93	0.92
	R² marginal	0.37	0.42			0.62	0.72		0.37	0.34	0.35	0.73	0.74
	ICC	0.85	0.87			0.75	0.77		0.83	0.85	0.85	0.73	0.69
	RMSE	0.04	0.04			0.05	0.05		0.04	0.04	0.04	0.06	0.06
	Sigma	0.05	0.05			0.06	0.06		0.05	0.04	0.04	0.07	0.07
Cubic splines / Cubic slope	R² conditional	0.85	0.87	0.94	0.95	0.91	0.94	0.86	0.86	0.86	0.83	0.91	0.90
	R² marginal	0.53	0.63	0.47	0.42	0.58	0.71	0.42	0.46	0.45	0.48	0.84	0.83
	ICC	0.68	0.66	0.88	0.92	0.78	0.78	0.75	0.74	0.74	0.68	0.42	0.42
	RMSE	0.04	0.05	0.05	0.05	0.05	0.05	0.04	0.04	0.04	0.04	0.07	0.07
	Sigma	0.05	0.05	0.05	0.05	0.06	0.06	0.05	0.05	0.04	0.05	0.08	0.08