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. 2023 Sep 25;2(4):e136. doi: 10.1002/imt2.136

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© 2023 The Authors. iMeta published by John Wiley & Sons Australia, Ltd on behalf of iMeta Science.

This is an open access article under the terms of the http://creativecommons.org/licenses/by/4.0/ License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

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Screening of Latilactobacillus sakei in vitro. (A) Flowchart of screening of L. sakei in vitro. (B) Impact of L. sakei on Caco‐2 cell viability after dextran sulfate sodium (DSS) stimulation. (C) Effects of L. sakei on TJ protein in Caco‐2 cells after DSS stimulation. (D) Influence of L. sakei on the expression of Caco‐2 cell‐related immune pathway after DSS stimulation. Different lowercase letters as superscripts (a–c) in the graph signify significant differences between groups (p < 0.05), determined by Tukey's multiple comparisons test (n = 6). JNK, c‐Jun N‐terminal kinase; NF‐κB, nuclear factor kappa B; TAK1, transforming growth factor beta‐activated kinase 1; TJ, tight junction; TRAF6, tumor necrosis factor receptor‐associated factor 6.