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. 2023 Sep 25;2(4):e136. doi: 10.1002/imt2.136

Table 1.

Latilactobacillus sakei with the effect of relieving colitis.

Strain Animal model Mechanism Year of publication Reference
L. sakei CVL‐001 DSS‐induced colitis Regulate immune response and intestinal integrity via gut microbiota modulation 2023 [35]
L. sakei probio65 TNBS‐induced colitis Reduce proinflammatory cytokines, regulate gut microbiota 2020 [36]
L. sakei S1 TNBS‐induced colitis Inhibit the NF‐κB pathway 2020 [37]
L. sakei OK67 HFD‐induced colitis Inhibit the NF‐κB pathway 2019 [38]
L. sakei K040706 DSS‐induced colitis Inhibit inflammation 2017 [39]
L. sakei K17 TNBS‐induced colitis Upregulate the expression of IL‐10 and TJ, inhibit the NF‐κB pathway 2016 [40]

Abbreviations: DSS, dextran sulfate sodium; HFD, high‐fat diet; IL, interleukin; NF‐κB, nuclear factor kappa B; TJ, tight junction; TNBS, 2,4,6‐trinitrobenzene sulfonic acid.