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. 2024 Apr 9;28:117. doi: 10.1186/s13054-024-04864-9

Correction: Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP) in patients with acute exacerbation of COPD: From the French OUTCOMEREA cohort

Louis‑Marie Galerneau 1,2,, Sebastien Bailly 2, Nicolas Terzi 1,2, Stephane Ruckly 3, Maite Garrouste‑Orgeas 4, Johanna Oziel 5, Vivien Hong Tuan Ha 6, Marc Gainnier 7, Shidasp Siami 8, Claire Dupuis 9, Jean‑Marie Forel 10, Anais Dartevel 1, Julien Dessajan 11, Christophe Adrie 12, Dany Goldgran‑Toledano 13, Virginie Laurent 14, Laurent Argaud 15, Jean Reignier 16, Jean‑Louis Pepin 2, Michael Darmon 17, Jean‑Francois Timsit 11; OUTCOME R. E. A. network
PMCID: PMC11005229  PMID: 38594747

Correction:Crit Care (2023) 27:359 10.1186/s13054-023-04631-2

Following publication of the original article [1], the authors identified an error in Table 1. The results were inverted between for variable No decrease in consciousness Day 1–Day 2. The correct table is given hereafter.

Table 1.

Baseline characteristics and mortality rate for patients with non-ventilator-associated ICU-acquired pneumonia admitted to an ICU for severe acute exacerbation of chronic obstructive pulmonary disease

No NV-ICU-AP (n = 802) NV-ICU-AP (n = 42) p value
Median [Q1; Q3] or n (percentage) Median [Q1; Q3] or n (percentage)
Baseline characteristics
Age (years) 70.7 [62.0; 78.1] 72.3 [67.6; 76.9] 0.33
Male sex, n (%) 499 (62.2) 31 (73.8) 0.13
BMI (kg/m2) 24.9 [20.8; 30.3] 23.9 [21.2; 30.1] 0.74
SAPS II score 34.0 [26.0; 42.0] 38.0 [30.0; 45.0] 0.05
Maximum SOFA Day 1- Day 2 4.0 [3.0; 6.0] 5.0 [3.0; 6.0] 0.06
Hospitalisation before ICU admission (yes), n (%) 264 (32.9) 20 (47.6) 0.05
Immunodeficiency (yes), n (%) 74 (9.2) 6 (14.3) 0.28
No decrease in consciousness Day 1- Day 2 (Glasgow Coma Scale = 15) 490 (61.1) 14 (33.1) < 0.01
MDR bacterial colonization, (yes), n (%) 47 (5.9) 3 (7.1) 0.73
COPD severity
Very Severe COPD, n (%) 173 (21.6) 1 (2.4) < 0.01
Trigger of the acute exacerbation of COPD
Respiratory infection, n (%) 524 (65.3) 29 (69.0) 0.74
Non-infectious respiratory causes, n (%) 165 (20.6) 8 (19.0)
Cardiac and thromboembolic events, n (%) 63 (7.9) 4 (9.5)
Others, n (%) 50 (6.2) 1 (2.4)
Therapeutic limitation
Limitation of therapeutic effort at admission to ICU, (yes) n (%) 63 (7.9) 3 (7.1) 0.87
Corticosteroid therapy
Use of corticosteroids therapy at admission, (yes) n (%) 302 (37.7) 12 (28.6) 0.24
Antibiotic therapy
Use of antibiotic therapy at admission, (yes) n (%) 561 (70.0) 25 (59.5) 0.15
Gastroprotective agents
Use of gastroprotective agents at admission, (yes) n (%) 411 (51.2) 22 (52.4) 0.89
Enteral nutrition
Use of enteral nutrition at admission, (yes) n (%) 99 (12.3) 10 (23.8) 0.03
Lengths of stay
ICU Length of stay (days) 6.0 [5.0; 10.0] 24.5 [14.0; 37.0] < 0.01
Hospital Length of stay (days) 18.0 [12.0; 30.0] 37.0 [22.0; 59.0] < 0.01
Mortality
ICU Mortality rate, n (%) 73 (9.1) 16 (38.1) < 0.01
Hospital Mortality rate, n (%) 123 (15.3) 18 (42.9) < 0.01
Mortality at Day 28, n (%) 96 (12.0) 10 (23.8) 0.02
Non-ventilator-associated ICU-acquired pneumonia
Day of first diagnosis of NV-ICU-AP (days in ICU) 6.0 [4.0; 11.0]
Day of first diagnosis of NV-ICU-AP (days in hospital) 7.5 [5.0; 16.0]
NV-ICU-AP requiring intubation, (yes) n (%) 32 (76.2)

Very Severe COPD = Oxygen therapy at home or NIV at home or Airflow limitation Stage 4. The use of corticosteroids therapy at admission was defined as a daily dose ≥ 0.5 mg/kg of prednisone or equivalent prescribed during the first 24 h after admission in ICU for the current AECOPD. Immunodeficiency was defined by the presence of aplasia, corticosteroid therapy for more than one month or at a dose > 2mg/kg of prednisone equivalent, chemotherapy, human immunodeficiency virus (HIV) at the acquired immunodeficiency syndrome (AIDS) stage or organ transplantation. Bacterial colonisation was defined by the presence of MDROs on screening samples taken on admission in ICU. These MDROs correspond to methicillin-resistant Staphylococcus aureus, extended-spectrum β-lactamase–producing Enterobacteriaceae, AmpC-producing Enterobacteriaceae, and Pseudomonas aeruginosa resistant to ticarcillin and/or imipenem and/or ceftazidime in the bacteriological samples

ICU, Intensive Care Unit; BMI, Body Mass Index, SAPS II, Simplified Acute Physiology Score II, SOFA Score, Sequential Organ Failure Assessment Score; COPD, Chronic Obstructive Pulmonary Disease, NV-ICU-AP, Non-ventilator-associated Intensive Care Unit Acquired Pneumonia

The incorrect Table 1 values are:

In the No NV-ICU-AP population, the number of patients with No decrease in consciousness Day 1–Day 2 (Glasgow Coma Scale = 15) is 312 (38.9%)

In the NV-ICU-AP population, the number of patients with No decrease in consciousness Day 1–Day 2 (Glasgow Coma Scale = 15) is 28 (66.7%)

The correct Table 1 values are:

In the No NV-ICU-AP population, the number of patients with No decrease in consciousness Day 1–Day 2 (Glasgow Coma Scale = 15) is 490 (61.1%)

In the NV-ICU-AP population, the number of patients with No decrease in consciousness Day 1–Day 2 (Glasgow Coma Scale = 15) is 14 (33.1%)

Table 1 has been updated in this correction article and the original article [1] has been corrected.

Footnotes

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Reference

  • 1.Galerneau LM, Bailly S, Terzi N, et al. Non-ventilator-associated ICU-acquired pneumonia (NV-ICU-AP) in patients with acute exacerbation of COPD: From the French OUTCOMEREA cohort. Crit Care. 2023;27:359. doi: 10.1186/s13054-023-04631-2. [DOI] [PMC free article] [PubMed] [Google Scholar]

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