Table 1:
Demographics of subjects.
| RNAseq Study (Figures 1&2) | Control (N=12) |
FTDtau (N=12) |
Difference between groups |
|---|---|---|---|
| Age - Mean (SD) | 62.3 (9.27) | 60.9 (6.32) | NS (t = 0.14, df = 17.83, p = 0.89) |
| Sex (F) | 5 (41.7%) | 5 (41.7%) | NS (χ squared=0, df=1, p=1) |
| RIN - Mean (SD) | 6.28 (0.79( | 5.95 (0.98) | NS (t = 1.69, df = 20.23, p = 0.11) |
| IHC study (Figure 3) | Control (N=11) |
FTDtau (N=11) |
|
| Age - Mean (SD) | 63.6 (9.97) | 61.4 (7.03) | NS (t = 0.62, df = 17.97, p = 0.54) |
| Sex (F) | 5 (45.5%) | 5 (45.5%) | NS (χ squared=0, df=1, p=1) |
| IHC study (Figures 4&5) | Control (N=9) |
FTDtau (N=7) |
|
| Age - Mean (SD) | 63.7 (9.23) | 62.6 (7.68) | NS (t = 0.26, df = 13.9, p = 0.80) |
| Sex (F) | 3 (33.3%) | 3 (43.9%) | NS (χ squared=0, df=1, p=1) |
| RNAseq age study (Figure S1) | Young control (<65) (N=10) |
Older control (>65) (N=11) |
|
| Age - Mean (SD) | 46.9 (8.96) | 79.6 (10.7) | *(t = −7.62, df = 18.89, p < 0.0001) |
| Sex (F) | 3 (30%) | 6 (54.5%) | NS (χ squared=048, df=1, p=0.49) |
| RIN - Mean (SD) | 6.58 (0.63) | 6.44 (0.99) | NS (t = 0.40, df = 17.10, p=0.69) |
NS = not significant
*
p < 0.05