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Effects of Punica granatum on acne vulgaris.
| Punica granatum Formulation | Effect | Model | Material | Dosage/Concentration | Mechanism | Study |
|---|---|---|---|---|---|---|
| Acetone extract | Antibacterial activity | Testosterone-induced accumulation of epithelial cells and keratin, anti-lipase activity for simulation of sebum accumulation | Wistar rats, HaCaT cells, heat-killed P. acnes | 0.1–10 mg/site, 0.25–1 mg, 2.5–10 mg |
Shrinkage and damage of P. acnes and S. aureus and inhibition of lipase activity | Lee et al. [30] |
