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. 2024 Apr 3;629(8010):136–145. doi: 10.1038/s41586-024-07278-3

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© The Author(s) 2024

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a, Comparison of the length of the kinetochore site, marked by hypomethylated DNA and CENP-A-containing chromatin, between the CHM1 and CHM13 centromeres. n = 28 and 25 kinetochore sites for the CHM1 and CHM13 centromeres, respectively. Data are mean ± s.e.m. Statistical analysis was performed using a two-sided Kolmogorov–Smirnov test; NS, not significant. b, The difference in the position of the kinetochore among the CHM1 and CHM13 centromeres. c, Comparison of the CHM1 and CHM13 chromosome 6 centromeres, which differ in kinetochore position by 2.4 Mb.