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[Preprint]. 2024 Apr 25:2024.04.25.591187. [Version 1] doi: 10.1101/2024.04.25.591187

Table 2.

Ligand-observed 1H CPMG NMR signal attenuation of hit compounds (100 μM). Error reported is standard deviation of two biological replicates. Individual spectra can be found in the Supplementary Information.

Compound Signal attenuation (%) Compound Signal attenuation (%)
6 58.8 ± 6.5 12 95.8 ± 5.90
7 17.1 ± 11.4 13 28.0 ± 4.0
8 55.0 ± 7.9 14 41.7 ± 1.1
9 5.45 ± 4.46 15 20.1 ± 10.0
10* 43.7 ± 10.2 16 33.7 ± 3.4
11 33.4 ± 4.7 17 49.7 ± 2.1

Potential compound aggregation.