Table 1. Observed crude, age-adjusted, and excess deaths for all causes, all cancers, and each cancer type with excess mortality rates during the pandemic in 2020, 2021, and 2022.
Each cancer type is listed in decreasing order of the number of deaths in 2022.
Excess mortality = (observed AMR - predicted AMR) / predicted AMR * 100 (%). (Predicted AMRs based on the pre-pandemic years 2010-2019 were calculated using logistic regression.)
Symbol ⁑ for >99%, * >95% upper, ‡<99%, †<95% lower prediction interval (PI)
| Cause of death and ICD-10 codes | Crude number of deaths | Age-adjusted number of deaths | Excess number of deaths (age-adjusted) | Excess mortality (age-adjusted) | |||||||||
| 2020 | 2021 | 2022 | 2020 | 2021 | 2022 | 2020 | 2021 | 2022 | 2020 | 2021 | 2022 | ||
| All-cause of deaths | 1,372,648 | 1,439,809 | 1,568,961 | 1,206,126 | 1,244,976 | 1,320,768 | -28,126 | 25,453 | 115,799 | -2.3%‡ | 2.1%⁑ | 9.6%⁑ | |
| Malignant neoplasms C00-C97 | 378,356 | 381,497 | 385,787 | 345,248 | 345,625 | 344,114 | -1,379 | 3,870 | 7,162 | -0.4% | 1.1%* | 2.1%⁑ | |
| Subclassification | Malignant neoplasm of trachea, bronchus and lung C33–C34 | 75,581 | 76,212 | 76,664 | 68,721 | 68,832 | 68,292 | -352 | 672 | 1,033 | -0.5% | 1.0% | 1.5% |
| Malignant neoplasm of colon, sigmoid, and rectum C18-C20 | 51,784 | 52,416 | 53,088 | 47,303 | 47,498 | 47,338 | -859 | -380 | -259 | -1.8% | -0.8% | -0.5% | |
| Malignant neoplasm of stomach C16 | 42,318 | 41,624 | 40,711 | 38,388 | 37,458 | 35,940 | -199 | 366 | 286 | -0.5% | 1.0% | 0.8% | |
| Malignant neoplasm of pancreas C25 | 37,674 | 38,578 | 39,468 | 34,590 | 35,249 | 35,593 | 296 | 651 | 688 | 0.9%* | 1.9%⁑ | 2.0%⁑ | |
| Other remaining malignant neoplasm in C00–C97 | 28,592 | 28,934 | 29,646 | 26,024 | 26,065 | 26,273 | -115 | 149 | 579 | -0.4% | 0.6% | 2.3% | |
| Malignant neoplasm of liver and intrahepatic bile ducts C22 | 24,839 | 24,102 | 23,621 | 22,561 | 21,708 | 20,960 | -42 | 161 | 421 | -0.2% | 0.7% | 2.0% | |
| Malignant neoplasm of gallbladder and other parts of biliary tract C23–C24 | 17,772 | 18,172 | 17,758 | 15,810 | 15,990 | 15,303 | -255 | 333 | 43 | -1.6% | 2.1% | 0.3% | |
| Malignant neoplasm of breast C50 | 14,650 | 14,803 | 15,911 | 14,089 | 14,185 | 15,109 | -558 | -631 | 122 | -3.8%† | -4.3%† | 0.8% | |
| Malignant lymphoma C81–C86 | 13,995 | 13,997 | 14,230 | 12,591 | 12,507 | 12,437 | 239 | 64 | -98 | 1.9% | 0.5% | -0.8% | |
| Malignant neoplasm of prostate C61 | 12,758 | 13,216 | 13,440 | 10,775 | 10,981 | 10,835 | 131 | 547 | 604 | 1.2% | 5.3%* | 5.9%* | |
| Malignant neoplasm of esophagus C15 | 10,978 | 10,958 | 10,918 | 10,298 | 10,248 | 10,105 | -381 | -226 | -170 | -3.6% | -2.2% | -1.7% | |
| Leukemia C91–C95 | 8,983 | 9,120 | 9,758 | 8,280 | 8,397 | 8,868 | -16 | 143 | 656 | -0.2% | 1.7% | 8.0%* | |
| Malignant neoplasm of bladder C67 | 9,166 | 9,443 | 9,597 | 8,060 | 8,196 | 8,114 | -181 | -68 | -171 | -2.2% | -0.8% | -2.1% | |
| Malignant neoplasm of lip, oral cavity and pharynx C00–C14 | 7,826 | 8,000 | 8,429 | 7,257 | 7,364 | 7,636 | -46 | 92 | 395 | -0.6% | 1.3% | 5.5%* | |
| Malignant neoplasm of uterus C53–C55 | 6,806 | 6,818 | 7,156 | 6,568 | 6,589 | 6,877 | -73 | -86 | 168 | -1.1% | -1.3% | 2.5% | |
| Malignant neoplasm of ovary C56 | 4,875 | 5,081 | 5,182 | 4,732 | 4,928 | 4,989 | 114 | 347 | 442 | 2.5% | 7.6%⁑ | 9.7%⁑ | |
| Other malignant neoplasms of lymphoid, hematopoietic,etc. C88–C90, C96 | 4,295 | 4,351 | 4,391 | 3,857 | 3,888 | 3,850 | -136 | -45 | -22 | -3.4% | -1.1% | -0.6% | |
| Malignant neoplasm of central nervous system C70–C72, C75.1–C75.3 | 2,847 | 3,054 | 3,106 | 2,729 | 2,944 | 2,966 | -165 | -46 | -120 | -5.7% | -1.5% | -3.9% | |
| Malignancy of skin C43–C44 | 1,707 | 1,718 | 1,806 | 1,532 | 1,512 | 1,546 | 8 | 1 | 47 | 0.6% | 0.1% | 3.2% | |
| Malignant neoplasm of larynx C32 | 781 | 795 | 798 | 714 | 721 | 707 | -62 | -27 | -15 | -8.0% | -3.6% | -2.1% | |