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. 2024 Apr 27;29(9):2020. doi: 10.3390/molecules29092020

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Structural formula of 3,8-dimethyl-5-(propan-2-yl)-N-propylazulene-1-carboxamide (a); 6H,7H,8H,9H,10H,11H-cycloocta[a]azulen-6-one (b); 5-fluoro-3-[(4-{2-[2-(hydroxymethyl)pyrrolidin-1-yl]ethyl}-3-methylazulen-1-yl)methylidene]-2,3-dihydro-1H-indol-2-one (c); N′-[(E)-(2-hydroxy-3-methoxyphenyl)methylidene]-3-methyl-7-(propan-2-yl)azulene-1-carbohydrazide (d); N′-[(E)-(3-hydroxynaphthalen-2-yl)methylidene]-3-methyl-7-(propan-2-yl)azulene-1-carbohydrazide (e); N′-[(E)-[4-(diethylamino)-2-hydroxyphenyl]methylidene]-3-methyl-7-(propan-2-yl)azulene-1-carbohydrazide (f); and 3-methyl-7-(propan-2-yl)-N-propylazulene-1-carboxamide (g), which are azulene derivatives with potential anticancer activity.